{"id":645,"date":"2023-06-12T07:49:37","date_gmt":"2023-06-12T07:49:37","guid":{"rendered":"https:\/\/sites.gtiit.edu.cn\/peng-xu-group\/?page_id=645"},"modified":"2023-06-27T03:04:15","modified_gmt":"2023-06-27T03:04:15","slug":"publications-2","status":"publish","type":"page","link":"https:\/\/sites.gtiit.edu.cn\/peng-xu-group\/publications-2\/","title":{"rendered":"Publications"},"content":{"rendered":"\t\t
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PUBLICATIONS<\/b><\/p>\n

-Theses<\/b><\/p>\n

Xu P<\/b>. (2013) Synthetic Pathway Design, Construction and Optimization: Towards Tailor-made Cell Factories for Flavonoids and Fatty Acids Production in E. coli<\/i>. Rensselaer Polytechnic Institute<\/i><\/span>, Troy, NY, USA. PhD dissertation.<\/p>\n

Refereed papers in professional journals<\/b><\/p>\n

-Published papers <\/b>(*corresponding authors)<\/b> <\/span><\/p>\n

Total citations: 5467, H-index: 39.<\/span>ORCID: 0000-0002-0999-8546; Web of Science Research ID: C-6440-2011<\/span><\/p>\n

\n<\/p>

1.     Azi F, Hong Y, Wu Z, Xu P*<\/b>. (2023) Synthetic consortium of Ganoderma lucidum<\/i> and Lactobacillus plantarum<\/i> for enhanced natural products biosynthesis. Biochemical Engineering Journal<\/i><\/span>. 108950.<\/p>\n

2.     Zhu J, Gu Y, Yan Y, Ma J and Xu P*<\/b>. (2023) Knocking out central metabolism genes to identify new targets and alternating substrates to improve lipid synthesis in Y. lipolytica<\/i>. Frontiers in Bioengineering and Biotechnology<\/i><\/span>. 11: 1098116.<\/p>\n

3.     Marsafari M, Azi F, Dou S and Xu P*<\/b>. (2022) Modular Co-Culture Engineering of Yarrowia Lipolytica<\/i> for Amorphadiene Biosynthesis. Microbial Cell factories<\/i><\/span> 21, 279.<\/p>\n

4.     J. Ma, Y. Gu, Xu P*<\/b>. (2022) Biosynthesis of cannabinoid precursor olivetolic acid in genetically engineered Yarrowia lipolytica. Communications Biology<\/i><\/span> 5 (1), 1-7.<\/p>\n

5.     Zeng Y, Hong Y, et al, and Xu P*<\/b>. (2022) Advanced genome-editing technologies enable rapid and large-scale generation of genetic variants for strain engineering and synthetic biology. Current Opinion in Microbiology<\/i><\/span> 69, 102175. <\/span><\/p>\n

6.     Liu H, Jin Y, Zhang R, Ning Y, Yu Y, Xu P*<\/b>, Deng L. (2022) Recent advances and perspectives on production of value-added organic acids through metabolic engineering. Biotechnology Advances<\/i><\/span>, 108076.<\/p>\n

7.     Liu Y and Xu P*<\/b>. (2022) Quantitative and analytical tools to analyze the spatiotemporal population dynamics of microbial consortia. Current opinion in Biotechnology<\/i><\/span>. 76, 102754. <\/span><\/p>\n

8.     Xu P*<\/b> and Zhou K. (2022) Editorial overview: Analytical biotechnology for healthcare, strain engineering, biosensing and synthetic biology. Current Opinion in Biotechnology<\/i><\/span> 77, 102765-102765. <\/span><\/p>\n

9.     F Azi, Z Li, Xu P*<\/b>, M Dong. (2022) Transcriptomic analysis reveals the antibacterial mechanism of phenolic compounds from kefir fermented soy whey against Escherichia coli<\/i> 0157: H7 and Listeria monocytogenes. International Journal of Food Microbiology<\/i><\/span> 383, 109953. <\/span><\/p>\n

10.  Qiu X, Gu Y, Du G, Zhang J, Xu P*<\/b> and Li J. (2021) Conferring thermotolerant phenotype to wild type Yarrowia lipolytica<\/i> improves cell growth and erythritol production. Biotechnology & Bioengineering<\/i><\/span>. 118 (8), 3117-3127.<\/p>\n

11.  Peng Z, Xu P<\/b>, Song Y, Du G, Zhang J and Chen J. (2021) Cysteine-Mediated Cyclic Metabolism Drives the Microbial Degradation of Keratin. ACS Sustainable Chemistry & Engineering<\/i><\/span>, <\/i>9 (29), 9861-9870<\/p>\n

12.  Gu Y<\/span> and Xu P<\/b>*. (2021) Synthetic yeast brews neuroactive compounds. Nature Chemical Biology<\/i><\/span>.17, 8-9. <\/span><\/p>\n

13.  Xu P<\/b>*. (2021) Dynamics of microbial competition, commensalism and cooperation and its implications for coculture and microbiome engineering. Biotechnology and Bioengineering<\/i><\/span>. 118 (1), 199-209. <\/span><\/p>\n

14.  Stephanopoulos G et al. Optimizing Oil Production in Oleaginous Yeast by Cell-Wide Measurements and Genome-Based Models. DOE-MIT-0008744. Report.<\/p>\n

15.  Xu P<\/b>*. (2021) In memory of Prof. Daniel I.C. Wang: Engineering Yarrowia lipolytica<\/i> for the production of plant-based lipids: technical constraints and perspectives for a sustainable cellular agriculture economy. Synthetic Biology Journal<\/i><\/span> 2 (4), 509-527<\/p>\n

16.  Tong Y<\/span>, Zhou J, Zhang L and Xu P*<\/b>. (2021) A Golden-Gate based cloning toolkit to build violacein pathway libraries in Yarrowia lipolytica<\/i>. ACS Synthetic Biology<\/i><\/span>, 10(1), 115-124.<\/i><\/p>\n

17.  Ma J<\/span>, Gu Y<\/span> and Xu P<\/b>*. (2020) A roadmap to engineering antiviral natural products synthesis in microbes. Current opinion in Biotechnology<\/i><\/span>. 66, 140-149.<\/p>\n

18.  Edwards H<\/span> and Xu P*<\/b> (2020). Unstructured kinetic models to simulate an arabinose switch that decouples cell growth from metabolite production. Synthetic & Systems Biotechnology<\/i><\/span>, 5(3): 222-229. <\/span><\/p>\n

19.  Ma J<\/span>, Gu Y<\/span> and Xu P<\/b>*. (2020) Synthetic biology, systems biology and metabolic engineering of Yarrowia lipolytica<\/i> toward a sustainable biorefinery platform. Journal of Industrial Microbiology & Biotechnology<\/i><\/span>. 47(9), 845-862. <\/span><\/p>\n

20.  Edwards H<\/span>, Yang Z<\/span>, and Xu P<\/b>* (2020). Characterization of Met25 as a Color Associated Genetic Marker in Yarrowia lipolytica<\/i>. Metabolic Engineering Communications<\/i><\/span>.11: e00147.<\/p>\n

21.  Liu H<\/span>, Wang F, Deng L and Xu P<\/b>*. (2020). Genetic and bioprocess engineering to improve squalene production in Yarrowia lipolytica<\/i>. Bioresource Technology<\/i><\/span>. 317:123991. <\/span><\/p>\n

22.  Gu Y<\/span>, Ma J<\/span>, Lv Y<\/span>, Zhu Y, Ding X and Xu P*<\/b>.<\/i> (2020) <\/b>Engineering Yarrowia lipolytica<\/i> as a chassis for de novo<\/i> synthesis of five aromatic-derived natural products and chemicals. ACS Synthetic Biology<\/i><\/span>. 9 (8), 2096\u20132106. <\/span><\/p>\n

23.  Lv Y<\/span>, Gu Y<\/span>, Xu J, Zhou J and Xu P<\/b>*. (2020) Coupling metabolic addiction with negative autoregulation to improve strain stability and pathway yield. Metabolic Engineering<\/i><\/span>. 61, 79-88. <\/span><\/p>\n

24.  Xu P*<\/b>, Masarfari M<\/span>, Zha J and Koffas MA*. (2020) Microbial co-cultures for flavonoid synthesis. Trends in Biotechnology<\/i><\/span>. 38 (7), 686-688. <\/span><\/p>\n

25.  Gu Y<\/span>, Ma J<\/span>, Zhu Y, Liu L and Xu P<\/b>* (2020). Refactoring Ehrlich pathway for high-yield 2-phenylethanol production in Yarrowia lipolytica<\/i>. ACS Synthetic Biology<\/i><\/span>. 9(3), 623-633. IF = 5.6 (cited by 12 times)<\/p>\n

26.  Qiu X<\/span>, Xu P<\/b>, Zhang J, and Li J (2020). Combining genetically-encoded biosensors with high throughput automatic strain screening to maximize erythritol production in Yarrowia lipolytica<\/i>. Metabolic Engineering<\/i><\/span>. 60, 66-76. IF = 7.3<\/p>\n

27.  Xu P<\/b>* (2020). Branch point control at malonyl-CoA node: A computational framework to uncover the design principles of an ideal genetic-metabolic switch. Metabolic Engineering Communications<\/i><\/span>. 10, e00127.<\/p>\n

28.  Marsafari M<\/span> and Xu P<\/b>*. (2020). Debottlenecking mevalonate pathway for antimalarial drug precursor amorphadiene biosynthesis in Yarrowia lipolytica<\/i>. Metabolic Engineering Communications<\/i><\/span>. 10, e00112. <\/span><\/p>\n

29.  Tong Y<\/span>, Zhou J, Zhang L and Xu P<\/b>* (2020) Engineering oleaginous yeast Yarrowia lipolytica<\/i> for violacein production: extraction, quantitative measurement and culture optimization. BioRxiv<\/i><\/span>. 10.1101\/687012.<\/p>\n

30.  Marsafari M<\/span>, Samizadeh H, Rabiei B, Mehrabi A, Koffas* M and Xu P<\/b>*. (2020). Biotechnological production of flavonoids: an update on plant metabolic engineering, microbial host and genetically encoded biosensors. Biotechnology Journal<\/i><\/span>. 15(8): 1900432. IF = 4.1<\/p>\n

31.  Liu Y, Li J, Ledesma-Amaro R, Xu P<\/b>, Du G and Liu L*. (2020) Towards next generation model microorganism chassis for biomanufacturing. Applied Microbiology and Biotechnology<\/i><\/span>. 104, 9095\u20139108. IF = 3.9<\/p>\n

32.  Marsafari M<\/span>, Ma J<\/span>, Koffas M and Xu P*<\/b>. (2020) Genetically encoded biosensors for analyzing and controlling cellular process in yeast. Current Opinion in Biotechnology<\/i><\/span>. 64, 175-182. IF = 8.3<\/p>\n

33.  Yang Z<\/span>, Edwards H<\/span> and Xu P<\/b>* (2020). CRISPR-Cas12a\/Cpf1-assisted precise, efficient and multiplexed genome-editing in Yarrowia lipolytica<\/i>. Metabolic Engineering Communications<\/i><\/span>. 10: e00112. (cited by 30 times)<\/p>\n

34.  Xu P<\/b>* (2020). Analytical solution for a hybrid Logistic-Monod cell growth model in batch and CSTR culture. Biotechnology and Bioengineering<\/i><\/span>. 117(3): 873-878. IF = 4.0. \u201cHighlights from Biotechnology and Bioengineering\u201d, 2020, https:\/\/onlinelibrary.wiley.com\/doi\/toc\/10.1002\/(ISSN)1097-0290<\/i>.<\/p>\n

35.  Gao C<\/span>, Xu P<\/b>, Ye C, Chen X and Liu L. (2019) Genetic Circuit-Assisted Smart Microbial Engineering. Trends in Microbiology<\/i><\/span>. 27(12): 1011-1024. IF = 13.6<\/p>\n

36.  Gao C<\/span>, Hou J, Xu P<\/b>, Guo L, Chen X, Hu G, Ye C, Edwards H, Chen J, Chen W and Liu L. (2019). Programmable biomolecular switches for rewiring flux in Escherichia coli<\/i>. Nature Communications<\/i><\/span>, 10:3751. IF = 12.1 (cited by 20 times)<\/p>\n

37.  Liu H<\/span>, Marsafari M<\/span>, Wang F, L Deng L and Xu P*<\/b> (2019). Engineering acetyl-CoA metabolic shortcut for eco-friendly production of polyketides triacetic acid lactone in Yarrowia lipolytica<\/i>. Metabolic Engineering<\/i><\/span>, 56: 60-68. IF = 7.3 (cited by 32 times)<\/p>\n

38.  Lv Y<\/span>, Marsafari M<\/span>, Koffas M, Zhou J and Xu P<\/b>* (2019). Optimizing oleaginous yeast cell factories for flavonoids and hydroxylated flavonoids biosynthesis. ACS Synthetic Biology<\/i><\/span>, 8(11), 2514-2523. IF = 5.6 (cited by 40 times)<\/p>\n

39.  Wan X<\/span>, Marsafari M<\/span> and Xu P*<\/b>. (2019) Engineering metabolite-responsive transcriptional factors to sense small molecules in eukaryotes: current state and perspectives. Microbial Cell Factories<\/i>.<\/span> 18 (1), 61. IF = 4.2 (cited by 29 times)<\/p>\n

40.  Lv Y<\/span>, Edwards H<\/span>, Zhou J and Xu P*<\/b>. (2019) Combining 26s rDNA and the Cre-loxP system for iterative gene integration and efficient marker curation in Yarrowia lipolytica<\/i>. ACS Synthetic Biology<\/i><\/span>. 8(3):568-576. IF = 5.6 (cited by 34 times)<\/p>\n

41.  Liu H<\/span>, Marsafari M<\/span>, Deng L and Xu P*<\/b>. (2019) Understanding lipogenesis by dynamically profiling transcriptional activity of lipogenic promoters in Yarrowia lipolytica<\/i>. Applied Microbiology and Biotechnology<\/i><\/span>. 103(7):3167\u20133179. IF = 3.9<\/p>\n

42.  Lv Y<\/span>, Qian S<\/span>, Zhou J, Chen J and Xu P*<\/b> (2019) Coupling feedback genetic circuits with growth phenotype for dynamic population control and intelligent bioproduction. Metabolic Engineering<\/i><\/span>, 54:109-116. IF = 7.3 (cited by 49 times)<\/p>\n

43.  Aris H<\/span>, Borhani S<\/span>, Cahn D<\/span>, O’Donnell C<\/span>, Tan E<\/span> and Xu P*<\/b>. (2019) Modeling transcriptional factor cross-talk to understand parabolic kinetics, bimodal gene expression and hysteresis behavior in biosensor design. Biochemical Engineering Journal<\/i><\/span>, 144: 209-216. IF = 3.5<\/p>\n

44.  Gao C<\/span>, Wang S, Hu GP, Guo L, Chen X, Xu P<\/b> and Liu L*. (2018) Engineering Escherichia coli<\/i> for malate production by integrating modular pathway characterization with CRISPRi-guided multiplexed metabolic tuning. Biotechnology and Bioengineering<\/i><\/span>. 115 (3), 661-672. IF = 4.0 (cited by 40 times)<\/p>\n

45.  Hu G, Zhou J, Chen X, Qian Y, Gao C, Guo L, Xu P<\/b>, Chen W, Chen J, Li Y, Liu L. (2018) Engineering synergetic CO2<\/sub>-fixing pathways for malate production. Metabolic engineering<\/i><\/span> 47, 496-504. IF = 7.3<\/p>\n

46.  Xu P*<\/b>.  (2018) Production of chemicals using dynamic control of metabolic fluxes. <\/b>Current Opinion in Biotechnology<\/i><\/span>, 53, 12-19. IF = 8.3 (cited by 77 times)<\/p>\n

47.  Jin EQ<\/span>, Engel J<\/span> and Xu P*<\/b>. (2018) Rapid evolution of regulatory element libraries for tunable transcriptional and translational control of gene expression. Synthetic and Systems Biotechnology<\/i><\/span>. 2(4), 295-301.<\/p>\n

48.  Johnson AO, Gonzalez-Villanueva M, Wong L<\/span>, Steinb\u00fcchel A, Tee KL, Xu P*<\/b>, Wong TS*. (2017) Design and application of genetically-encoded malonyl-CoA biosensors for metabolic engineering of microbial cell factories, Metabolic Engineering<\/i><\/span>, 44:253-264. IF = 7.3 (cited by 56 times)<\/p>\n

49.  Wong L<\/span>. Engel J<\/span>, Jin EQ<\/span>, Holdridge B<\/span> and Xu P*<\/b>. (2017) YaliBricks, a versatile genetic toolkit for streamlined and rapid pathway engineering in Yarrowia lipolytica<\/i>. Metabolic Engineering Communications<\/i><\/span>, 5: 68-77. IF = 7.3. (Cited by 60 times)<\/p>\n

50.  Xu P<\/b>, Qiao K and Stephanopoulos G*. (2017). Engineering oxidative stress defense pathways to build a robust lipid production platform in Yarrowia lipolytica<\/i>. Biotechnology and Bioengineering<\/i><\/span>, 114(7): 1521\u20131530. IF = 4.0 (Cited by 102 times). <\/span><\/p>\n

51.  Qiao K, Wasylenko T, Zhou K, Xu P<\/b> and Stephanopoulos G*. (2017). Lipid production in Yarrowia lipolytica<\/i> is maximized by engineering cytosolic redox metabolism. Nature Biotechnology<\/i><\/span>, 35, 173\u2013177. IF = 36.6 (Cited by 220 times). \u201cA step toward renewable diesel\u201d, reported by MIT news.<\/i> http:\/\/news.mit.edu\/2017\/yeast-convert-plant-sugars-oils-renewable-diesel-0116<\/span><\/a> <\/span><\/p>\n

52.  Xu P<\/b>, Rizzoni EA<\/span>, Sul SY<\/span> and Stephanopoulos G*. (2016) Improving metabolic pathway efficiency by statistical model based multivariate regulatory metabolic engineering. ACS Synthetic Biology<\/i><\/span>, 6 (1), 148\u2013158. IF = 5.6 (Cited by 75 times).<\/p>\n

53.  Xu P<\/b>, Qiao K, Ahn WK and Stephanopoulos G*. (2016) Engineering Yarrowia lipolytica<\/i> as a platform for synthesis of drop-in transportation fuels and oleochemicals. Proceedings of the National Academy of Sciences, U.S.A<\/i><\/span>., 113(39): 10848\u201353. IF = 9.4 (Cited by 238 times). \u201cYeast makes diesel-like fuels\u201d, featured by Nature Publishing Group, <\/i>http:\/\/www.nature.com\/nature\/journal\/v537\/n7621\/full\/537452e.html<\/i><\/span><\/a>. Oleaginous Yeasts Move One Step Closer to Becoming Industrial Biodiesel Producers\u201d reported by U.S. Department of Energy Office of Biological and Environmental Research, <\/i>https:\/\/public.ornl.gov\/site\/bernews\/search_news_action.cfm?id=1689&webid<\/i><\/span><\/a> <\/span><\/i><\/p>\n

54.  Silverman, A, Qiao K, Xu P<\/b> and Stephanopoulos G*. (2015) Functional overexpression and characterization of lipogenesis-related genes in the oleaginous yeast Yarrowia lipolytica<\/i>. Applied Microbiology and Biotechnology<\/i><\/span>. 100(8):3781-98. IF = 3.9 (Cited by 53 times).<\/p>\n

55.  Lim CG, Wong L, Bhan N, Dvora H, Xu P<\/b>, Koffas M*. (2015) Development of a recombinant Escherichia coli<\/i> strain for overproduction of the plant pigment anthocyanin. Applied and Environmental Microbiology<\/i><\/span>. 81(18):6276-84. IF = 3.9 (Cited by 57 times).<\/p>\n

56.  Trantas EA, Koffas MA, Xu P<\/b> and Ververidis F*. (2015) Biotechnology of flavonoids: Metabolic engineering with commercial applications when plants produce not enough or at all. Frontiers in Plant Science<\/i><\/span>, 6:7. IF = 4.4 (Cited by 77 times).<\/p>\n

57.  Bhan N, Li L, Cai C, Xu P<\/b>, Linhardt R and Koffas M*. (2015) Enzymatic formation of a resorcylic acid by creating a structure-guided single-point mutation in stilbene synthase. Protein Science<\/i><\/span>, 24: 167-173. IF = 3.9.<\/p>\n

58.  Xu P<\/b>, Li L, Zhang F, Stephanopoulos GN and Koffas MA*. (2014) Improving fatty acids production by engineering dynamic pathway regulation and metabolic control. Proceedings of the National Academy of Sciences, U.S.A.<\/i><\/span>, 111(31):11299-304. IF = 9.4 (Cited by 370 times). \u201cRensselaer Polytechnic Institute Researchers Develop New Method of Fatty Acid Production Via Dynamic Regulation\u201d, reported by RPI news.<\/i> https:\/\/news.rpi.edu\/content\/2014\/07\/22\/researchers-develop-new-method-fatty-acid-production<\/span><\/a> <\/span><\/p>\n

59.  Xu P<\/b>, Wang W, Li L, Bhan N, Zhang F and Koffas MA*. (2014) Design and kinetic analysis of a hybrid promoter-regulator system for malonyl-CoA sensing in E. coli. ACS Chemical Biology<\/i><\/span>, 9(2): 451-458. IF = 4.4. (Cited by 110 times).<\/p>\n

60.  Xu P<\/b>, Bhan N and Koffas MA*. (2013) Engineering plant metabolism into microbes: from systems biology to synthetic biology. Current Opinion in Biotechnology<\/i><\/span>. 24(2): 291-299. IF = 8.3 (Cited by 117 times).<\/p>\n

61.  Bhan N, Xu P<\/b> and Koffas MA*. (2013) Pathway and protein engineering approaches to produce novel and commodity small molecules. Current Opinion in Biotechnology<\/i><\/span>, 24(6): 1137-1143. IF = 8.3 (Cited by 58 times).<\/p>\n

62.  Wang W, Englaender J, Xu P<\/b>, Linhardt RJ, Koffas MA*. (2013) Expression of low endotoxin 3-O-sulfotransferase in B. subtilis<\/i> and B. megaterium<\/i>. Applied Biochemistry and Biotechnology<\/i><\/span>, 171(4): 954-962. IF = 1.6.<\/p>\n

63.  Xu P<\/b>, Gu Q; Wang W, Wong L, Bower A, Collins CH and Koffas MA*. (2013) Modular optimization of multi-gene pathway for fatty acids production in E. coli<\/i>. Nature Communications<\/i><\/span>, 4: 1409. IF = 12.4 (Cited by 386 times).<\/p>\n

64.  Bhan N, Xu P<\/b>, Khalidi O and Koffas MA*. (2013) Redirecting carbon flux into Malonyl-CoA to improve Resveratrol titers: Proof of concept for genetic interventions predicted by OptForce computational framework. Chemical Engineering Science<\/i><\/span>, 103: 109-114. IF = 3.9 (Cited by 50 times).<\/p>\n

65.  Xu P<\/b>, Vansiri A, Bhan N and Koffas MA*. (2012) ePathBrick: A synthetic biology platform for engineering metabolic pathways in E. coli<\/i>. ACS Synthetic Biology<\/i><\/span>, 1(7):256\u2013266. IF = 5.6 (Cited by 215 times).<\/p>\n

66.  Xu P<\/b>, Ranganathan S, Fowler Z, Maranas CD and Koffas MA*. (2011) Genome-scale metabolic network modeling results in minimal interventions that cooperatively force carbon flux towards malonyl-CoA. Metabolic Engineering<\/i><\/span>, 13(5): 578-587. IF = 7.3 (Cited by 275 times).<\/p>\n

67.  Zhang L, Ding Z, Xu P<\/b> et al. (2011) Methyl lucidenate F isolated from the ethanol-soluble-acidic components of G. lucidum is a novel tyrosinase inhibitor. Biotechnology and Bioprocess Engineering<\/i><\/span>, 16(3): 457-461. IF = 2.2.<\/p>\n

68.  Xu P<\/b> and Koffas MA*. (2010) Metabolic engineering of E. coli<\/i> for biofuel production, Biofuels<\/i><\/span>, 1(3): 493-504. (Cited by 30 times).<\/p>\n

69.  Zhang T, Xu P<\/b> et al. (2009) Identification of biological wort turbidity caused by microbial contamination of Gairdner barley. Journal of the American Society of Brewing Chemists<\/i><\/span>, 67(1): 33-37. IF = 1.2<\/p>\n

70.  Xu P<\/b>, Ding Z, Qian Z, Zhang K and Zhao C. (2008) Improved production of mycelial biomass and ganoderic acid by submerged culture of G. lucidum SB97 using complex media. Enzyme and Microbial Technology<\/i><\/span>, 42(4): 325-331. IF = 2.9 (Cited by 95 times).<\/p>\n

71.  Xu P<\/b>, Qian Z, Zhao CX. (2008) Kinetic analysis of exo-polysaccharide and ganoderic acid production by submerged culture of Ganoderma lucidum<\/i>. Chinese Journal of Applied & Environmental Biology<\/i><\/span>, 14(4): 562-565.<\/p>\n

72.  There are other more than 20 research articles published in Chinese journals from 2004 to 2009.<\/b><\/p>\n

\n<\/p>

Accepted or in press papers<\/b><\/p>\n

-Submitted papers <\/span><\/b><\/p>\n

73.  Ma J, Gu Y and Xu P*<\/b>. (2022) Biosynthesis of cannabinoid precursor olivetolic acid by overcoming rate-limiting steps in genetically engineered Yarrowia lipolytica<\/i>. Under review by Communications Biology.<\/p>\n

74.  Marsafari M, Azi F and Xu P*<\/b>. (2022) Modular Co-Culture Engineering of Yarrowia Lipolytica<\/i> for Amorphadiene Biosynthesis. Under review by Microbial cell factory<\/p>\n

75.  Xu P<\/b>*. (2020) Applying chemical reaction transition theory to predict the latent transmission dynamics of coronavirus outbreak in China. MedRxiv<\/i><\/span>, Under review. <\/span><\/p>\n

\n<\/p>

-Review papers<\/b><\/p>\n

\n<\/p>

76.  Tang L, Xu P<\/b><\/span>* and Zhang H. (2020) Editorial overview: tissue, cell and pathway engineering: programming biology for smart therapeutics, microbial cell factory and intelligent biomanufacturing. Current opinion in Biotechnology<\/i><\/span>. 66, iii-vi. <\/span><\/p>\n

77.  Xu P*<\/b><\/span> and Zhou K. (2022) Editorial overview: Analytical biotechnology for healthcare, strain engineering, biosensing and synthetic biology. Current opinion in Biotechnology<\/i><\/span>. 76, Article 102765.<\/p>\n

\n<\/p>

-Books <\/span><\/b><\/p>\n

78.  Analytical Biotechnology, Volume 76, Current Opinion in Biotechnology, Guest editor by Kang Zhou and Peng Xu. Published by Elsevier, 2022. IF = 10.3 Book link<\/span><\/a><\/p>\n

\n<\/p>

79.  Tissue, Cell and Pathway Engineering, Volume 66, Current Opinion in Biotechnology, Guest editor by Li Tang, Peng Xu and Haoran Zhang. Published by Elsevier, 2020. IF = 10.3 Book link<\/span><\/a><\/p>\n

\n<\/p>

-Chapters in books <\/span><\/b><\/p>\n

\n<\/p>

80.  Yang Z<\/span> and Xu P*<\/b>. (2021) Implementing CRISPR-Cas12a for Efficient Genome Editing in Yarrowia lipolytica<\/i>. Methods in Molecular Biology<\/i><\/span>, Ian Wheeldon and Mark Blenner (Eds): Yarrowia lipolytica<\/i>. Chapter 7. IF = <\/span><\/p>\n

81.  Sun W<\/span>, Yang Z and Xu P*<\/b>. (2021) Engineering Yarrowia lipolytica<\/i> for Production of Fatty Alcohols with YaliBrick Vectors. Methods in Molecular Biology<\/i><\/span>. Ian Wheeldon and Mark Blenner (Eds): Yarrowia lipolytica<\/i>. Chapter 11.<\/p>\n

82.  Wong L<\/span>, Holdridge B<\/span>, Engel J<\/span> and Xu P*<\/b>. (2018) Genetic tools for streamlined and accelerated pathway engineering in Yarrowia lipolytica<\/i>. Methods in Molecular Biology: Microbial Metabolic Engineering<\/i><\/span>, <\/i><\/b>155-177.<\/p>\n

83.  Xu P<\/b> and Koffas MA. (2013) Assembly of multi-gene pathways and combinatorial pathway libraries through ePathBrick vectors. Methods in Molecular Biology: Synthetic Biology<\/i><\/span>. 1073:107-29.<\/p>\n

\n<\/p>

Refereed papers in conference proceedings<\/b><\/p>\n

\n<\/p>

84.  Xu P<\/b>, Ranganathan S, Maranas C and Koffas M. (2011) An integrated computational and experimental study to increase the intracellular malonyl-CoA: application to flavanone synthesis. IEEE. 2011 IEEE 37th Annual Northeast Bioengineering Conference (NEBEC).<\/p>\n

\n<\/p>

Patents granted or submitted<\/b><\/p>\n

1.     Xu J, Xu P<\/b> and Lv Y. A molecular device to switch carbon flux and engineer naringenin addiction phenotype. China Patent grant No.: ZL 2019 1 1240 118.0<\/p>\n

2.     Stephanopoulos G. Qiao K, and Xu P<\/b>. Strain and bioprocess engineering for high-lipid production. U.S. Patent Application No.: 15\/296,148; WO2017070065A1<\/p>\n

\n<\/p>

Research reports and other publications <\/span><\/b><\/p>\n

-List of selected publications<\/b><\/p>\n

\n<\/p>

1.     Lv Y<\/span>, Gu Y<\/span>, Xu J, Zhou J and Xu P<\/b><\/span>*. (2020) Coupling metabolic addiction with negative autoregulation to improve strain stability and pathway yield. Metabolic Engineering<\/i><\/span>. 61, 79-88. This article reports the engineering of feedback control system in yeast to improve strain stability. Dr. Xu is the leading PI.<\/p>\n

2.     Gu Y<\/span>, Ma J<\/span>, Lv Y<\/span>, Zhu Y, Ding X and <\/b>Xu P<\/b><\/span>*<\/b>.<\/i> (2020) <\/b>Engineering Yarrowia lipolytica<\/i> as a chassis for de novo<\/i> synthesis of five aromatic-derived natural products and chemicals. ACS Synthetic Biology<\/i><\/span>. 9 (8), 2096\u20132106. This article reported the engineering of Y. lipolytica<\/i> to produce five high-value aromatic compounds. <\/span><\/p>\n

3.     Xu P<\/b>* (2020). Analytical solution for a hybrid Logistic-Monod cell growth model in batch and CSTR culture. Biotechnology and Bioengineering<\/i><\/span>. 117(3): 873-878. This article reported a new model and analytical solution to describe cell growth. <\/span><\/p>\n

4.     Liu H<\/span>, Marsafari M<\/span>, Wang F, L Deng L and Xu P*<\/b> (2019). Engineering acetyl-CoA metabolic shortcut for eco-friendly production of polyketides triacetic acid lactone in Yarrowia lipolytica<\/i>. Metabolic Engineering<\/i><\/span>, 56: 60-68. This paper reported the upgrading of low-cost acetic acids to high-value polyketides with genetically-engineered yeast. <\/span><\/p>\n

5.     Xu P<\/b>, Qiao K, Ahn WK and Stephanopoulos G*. (2016) Engineering Yarrowia lipolytica<\/i> as a platform for synthesis of drop-in transportation fuels and oleochemicals. Proceedings of the National Academy of Sciences, U.S.A<\/i><\/span>., 113(39): 10848\u201353. Dr. Xu is the first author and major contributor for this article.<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

PUBLICATIONS -Theses Xu P. (2013) Synthetic Pathway Design, Construction and Optimization: Towards Tailor-made Cell Factories for Flavonoids and Fatty Acids Production in E. coli. Rensselaer Polytechnic Institute, Troy, NY, USA. PhD dissertation. Refereed papers in professional journals -Published papers (*corresponding authors)  Total citations: 5467, H-index: 39.ORCID: 0000-0002-0999-8546; Web of Science Research ID: C-6440-2011 1.     Azi …<\/p>\n

Publications<\/span> Read More »<\/a><\/p>\n","protected":false},"author":328,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":[],"_links":{"self":[{"href":"https:\/\/sites.gtiit.edu.cn\/peng-xu-group\/wp-json\/wp\/v2\/pages\/645"}],"collection":[{"href":"https:\/\/sites.gtiit.edu.cn\/peng-xu-group\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.gtiit.edu.cn\/peng-xu-group\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.gtiit.edu.cn\/peng-xu-group\/wp-json\/wp\/v2\/users\/328"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.gtiit.edu.cn\/peng-xu-group\/wp-json\/wp\/v2\/comments?post=645"}],"version-history":[{"count":3,"href":"https:\/\/sites.gtiit.edu.cn\/peng-xu-group\/wp-json\/wp\/v2\/pages\/645\/revisions"}],"predecessor-version":[{"id":878,"href":"https:\/\/sites.gtiit.edu.cn\/peng-xu-group\/wp-json\/wp\/v2\/pages\/645\/revisions\/878"}],"wp:attachment":[{"href":"https:\/\/sites.gtiit.edu.cn\/peng-xu-group\/wp-json\/wp\/v2\/media?parent=645"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}