Guidelines on Application for Special Projects on Nanotechnology under the 2022-2023 Guangdong Key Field R&D Program
According to the 14th Five-Year Plan for Scientific and Technological Innovation in Guangdong Province and the 14th Five-Year Action Plan for the Guangdong Key Field R&D Program, Guangdong will conduct special R&D projects in the field of nanotechnology to address key technological, material, and equipment challenges, in an effort to turn the Guangdong-Hong Kong-Macao Greater Bay Area (GBA) into a hub for nanotechnology innovation.
These special projects will be conducted through “province-district collaboration”, pursuing four research directions with a focus on technology industrialization and 15 research directions in other areas, mainly nanomaterials, nanodevices, and nanomedicine. For the area of industrialization, the national nanotechnology innovation research institute of the GBA will lead the implementation of major projects that involve mature technology and can effectively drive industrial development and meet the urgent needs of Guangdong. For other areas, priority is given to future-oriented projects that fit into the industrial landscape of Guangdong and have the potential to boost the nano-industry in the region. Projects in three research directions will receive support from both Guangdong Province and Huangpu District in Guangzhou. These projects must be led by enterprises located in the aforesaid district, or they must translate the research results into industry solutions applied in the district.
In principle, only one project will receive support for each research direction, a project generally lasts two to three years, and there should be no more than six joint applicants for each project. The project proposal must cover all the research content listed under the corresponding research direction. Only when the project meets all the performance indicators listed under the research direction can it pass the acceptance inspection.
- Industrialization (No.: 20220119)
(Omitted)
- Other areas (No.: 20220120)
These special projects focus on core technology R&D and industrial application research in nanomaterials, nanodevices and nanomedicine. There are a total of 15 research directions, and three of them will receive support from both the province and the district.
Direction 2.1: Key technology and application R&D of high-strength micro/nano super-amphiphobic metal coatings (province-district collaboration)
1. Research content
Investigate the relationship between the micro/nano composite structure and the super-amphiphobic property of metal coatings, as well as the binding force, wear resistance, stability, and other properties of multi-functional polymer super-amphiphobic coatings and their mechanisms; develop specialized equipment for microwave plasma chemical vapor deposition (MPCVD) and electrostatic spraying; use MPCVD and electrostatic spraying to develop and mass-produce micro/nano super-amphiphobic multilayer coatings and multi-scale/graded micro/nano composite super-amphiphobic protective coatings.
2. Requirements
The project will receive support from both the province and the district. To be eligible for this support, the project must be led by an enterprise located in Huangpu District, Guangzhou, or must translate its research results into industry solutions applied in the district.
3. Funding amount
The funding amount is capped at RMB 6 million.
Direction 2.2: R&D and industrial application of biomass nanocellulose and its derivative coatings (province-district collaboration)
1.Research content
Study the internal microstructure regulation of biomass materials, and develop technology for the dissociation and extraction of high-strength, high-modulus, high-aspect ratio, and high-crystallinity biomass nanocellulose under mild conditions; investigate the role and mechanism of biomass nanocellulose in the emulsification, dispersion, and drying of water-based eco-friendly coatings, explore methods for preparing eco-friendly additives to produce biomass nanocellulose-based zero-VOC coatings, and complete lab-scale testing, pilot production and process validation of these coatings; study the application technology of biomass nanocellulose-based eco-friendly coatings and the evaluation methods for these coatings according to national coating standards, in order to produce highly effective coating products.
2. Requirements
The project will receive support from both the province and the district. To be eligible for this support, the project must be led by an enterprise located in Huangpu District, Guangzhou, or must translate its research results into industry solutions applied in the district.
3. Funding amount
The funding amount is capped at RMB 10 million.
Direction 2.3: Development and application of efficient nano-catalytic detoxification technology for toxic organic compounds
1.Research content
Study the synthesis and surface properties of asymmetrically distributed electron-induced nano catalysts in the Fenton oxidation system, and investigate the role of internal electronic self-circulation regulation and nanoparticle size in improving the utilization efficiency, with the aim of solving the problem of metal ion loss and generating a stable, green catalyst; take typical toxic organic compounds such as antibiotics, pesticides, and chlorinated aromatics as the research object to study the Fenton-like catalytic method and selectively degrade pollutants according to their structure to enable the efficient, rate-controlled, and directed oxidation and degradation of detoxified organic compounds; develop integrated technologies and equipment based on efficient nano-catalytic detoxification; conduct pilot trials of the research results for efficient and selective treatment of toxic organic pollutants, without loss or pollution.
2. Requirements
The project must be led by an enterprise located in Guangdong Province. Joint research by enterprise-university-research institute consortium is encouraged.
3. Funding amount
The funding amount is capped at RMB 10 million.
Direction 2.5: Research, development and industrialization of surface nano-coatings for preventing the adhesion of marine microorganisms
1.Research content
Carry out research on the mechanism of adhesion of marine microorganisms on different nano-coating surfaces, study the correlation between surface nanostructure and microorganism adhesion, and develop novel antifouling resin materials and eco-friendly antifouling agents; carry out research on the preparation process of novel antifouling coatings, study the correlation between the composition and structure of antifouling coating surfaces and their antifouling performance, to improve key properties such as coating life, degradability and renewal rate; explore the technology for the mass production and application of novel nano-coatings to enable large-scale and stable production of novel nano-coatings, and conduct pilot trials of the nano-coatings on marine equipment such as ships and marine cages.
2. Requirements
The project must be led by an enterprise located in Guangdong Province. Joint research by enterprise-university-research institute consortium is encouraged.
3. Funding amount
The funding amount is capped at RMB 10 million.
Direction 2.6: Preparation and application of functional nano-metal oxides
1. Research content
Carry out computer simulation technology-based research on the controlled preparation of nano-oxides such as nano-alumina and nano-titanium dioxide by gas-phase method, establish the model of the reaction device structure – reaction temperature field – airflow state – particle structure – performance relationship, and realize the adjustment and optimization of the combustion reaction by gas-phase method; carry out research on the key technology for the continuous preparation of nano-oxides by gas-phase method, study the use of high-energy technology in regulating the size of nanoparticle agglomerates and achieving efficient gas-solid separation, and develop key equipment for the controlled preparation of nano-oxides; conduct systematic pilot trials of nano-oxides in catalytic degradation of toxic substances and high-end cosmetics.
2. Requirements
The project must be led by an enterprise located in Guangdong Province. Joint research by enterprise-university-research institute consortium is encouraged.
3. Funding amount
The funding amount is capped at RMB 6 million.
Direction 2.7: Development of high-threshold-voltage low-gate-leakage normally-off GaN high-electron-mobility transistors
1.Research content
Carry out research on GaN high-electron-mobility transistor (HEMT) structure to reduce gate leakage and improve the gate withstand voltage under the condition of threshold voltage stability; study high-quality GaN epitaxial growth technology, high-quality P-GaN epitaxy technology, gate etching technology, surface passivation technology, GaN ohmic contact technology, etc. to form a mass production process; investigate the reliability of the electrical properties of the device and the time-dependent dielectric breakdown (TDDB) characterizing the gate, and realize the application of the device in the field of consumer electronics with power of 125-200 W, industrial electronics with voltage of 650 V, data center power supply and inverter module of new energy vehicle charging pile.
2. Requirements
The project must be led by an enterprise located in Guangdong Province. Joint research by enterprise-university-research institute consortium is encouraged.
3. Funding amount
The funding amount is capped at RMB 10 million.
Direction 2.8: Development of novel nanostructure-based enhanced spectral detection devices
1. Research content
Develop high-precision frequency selection technology based on nano-optical resonance mechanism and a spectral scan sampling technology based on dynamic tuning to achieve high-precision on-chip integrated spectral tuning in a wide wave band range; develop an in-situ integrated device architecture of nano-optical dispersion unit and photoelectric detection unit, establish an efficient spectral reconstruction method in a wide wavelength range, and develop on-chip electrical signal output spectral detection technology; develop high-precision large-area manufacturing technology for nano-micron optical resonance structures, solve the challenge of integrating nano-optical structure, tuning unit and detection unit, and develop nanostructure-based enhanced spectral detection chip components.
2. Requirements
The project must be led by an enterprise located in Guangdong Province. Joint research by enterprise-university-research institute consortium is encouraged.
3. Funding amount
The funding amount is capped at RMB 10 million.
Direction 2.9: Development of high-efficiency materials and plane array components for solar-blind UV detectors
1. Research content
Develop nanocrystalline Ga2O3 thin film preparation technology that enables control over the size, density and structure of nanocrystals; regulate the defects and optimize the performance of materials, and investigate the influence of intrinsic defects in nanocrystals on photoelectric synergistic regulation and its intrinsic mechanism; conduct research on the parameters and preparation process of nanocrystalline materials and detectors to achieve large-scale production of solar-blind UV detection units and array components; develop a high-performance active-matrix plane array imaging system and form typical use cases.
2. Requirements
The project can be led by an enterprise or a public institution located in Guangdong Province. Joint research by enterprise-university-research institute consortium is encouraged.
3. Funding amount
The funding amount is capped at RMB 6 million.
Direction 2.10: Development of novel nano-flexible tactile sensors and integrated systems
1. Research content
Carry out research on the technology for manufacturing highly flexible, thin and durable pressure sensors and the preparation process of nano-sensitive materials with high pressure sensitivity to improve the sensitivity, resolution and precision of flexible sensors; study the preparation process of high-density flexible pressure sensor arrays, improve the pixel resolution of sensor arrays and the detection stability of sensor at 25°C to 45°C, and substantially improve the reliability and stability of sensor arrays; study the failure mechanism of flexible sensor arrays in a complex multi-stress environment and explore a comprehensive approach to reliability evaluation, develop a method for mass production of homogeneous nano-pressure-sensitive materials and sensor electrodes that can be applied to wearable devices for vital sign monitoring and disease surveillance, and realize the mass production of high-sensitivity and high-stability tactile sensors and integrated systems.
2. Requirements
The project must be led by an enterprise located in Guangdong Province. Joint research by enterprise-university-research institute consortium is encouraged.
3. Funding amount
The funding amount is capped at RMB 6 million.
Direction 2.11: Development of high-energy-density dielectric nanocomposites and pulsed energy storage devices
1.Research content
Modify inorganic dielectric nanocomposite and design polymer composites such as polyvinylidene difluoride (PVDF), and conduct research on the preparation of dielectric composites as well as their energy storage performance and temperature stability; carry out the preparation of multilayer heterogeneous dielectric energy storage composites and energy storage performance studies, study the interfacial polarization, breakdown mechanism and coupling effect of dielectric composites, and probe into the effect of local electric field distribution on the polarization strength and breakdown strength of interlayer interfaces; carry out the design, R&D and mass production of large-area composite dielectric films, explore the technology for preparing self-healing multilayer nano-metal electrodes, and realize the development and mass production of high-energy-storage-density pulsed power capacitors.
2. Requirements
The project must be led by an enterprise located in Guangdong Province. Joint research by enterprise-university-research institute consortium is encouraged.
3. Funding amount
The funding amount is capped at RMB 6 million.
Direction 2.12: Development of polymer nano-hemodialysis membrane
1. Research content
Carry out the research and development of homegrown polyethersulfone polymer nano-hemodialysis membranes with nano-microstructures, and study the bioactive modification technology, surface modification technology and multi-membrane synthesis technology applied on the membrane surface, to improve the hemocompatibility of hemodialysis membrane; study the preparation process and key preparation technology of high-flux dialysis membrane and low-flux dialysis membrane to achieve the industrialization and mass production of homegrown hemodialysis membranes; carry out clinical trial studies on high-flux dialysis membrane and low-flux dialysis membrane in hemodialysis to form examples and use cases.
2. Requirements
The project must be led by an enterprise located in Guangdong Province. Joint research by enterprise-university-research institute consortium is encouraged.
3. Funding amount
The funding amount is capped at RMB 10 million.
Direction 2.13: Development of a novel immunoregulatory composite nanosystem (province-district collaboration)
1. Research content
Study the universal novel manganese-based immunoregulatory composite nanosystem targeting encephalitis B virus and explore the technology for precise regulation of structure-activity relationship between antigen and nanosystem, to reduce immunizing dose and improve vaccine production capacity; investigate the universal novel composite immunoregulatory nanosystem based on continuous microfluidic preparation technology, and realize the industrialization of the process, validation and quality control of lab-scale test and pilot production; carry out technical studies on quality, safety and vaccine efficacy, and rapidly promote the clinical assessment and industrialization.
2. Requirements
The project will receive support from both the province and the district. To be eligible for this support, the project must be led by an enterprise located in Huangpu District, Guangzhou, or must translate its research results into industry solutions applied in the district.
3. Funding amount
The funding amount is capped at RMB 6 million.
Direction 2.14: Development of in vitro tumor marker detection chip and equipment
1. Research content
Carry out research on novel micro/nano-structured plasmon chips with high Q value (Q factor) and strong local field, and explore the technology for applying the micro/nano-structured plasmon chip with strong local field in specificity detection; study the surface modification technology of local surface plasmon chip that enables the specificity detection of tumor markers (AFP, CEA, CA199, CA125 and NSE); carry out research on the nano-preparation technology for mass production of plasmon chips with high accuracy and high repeatability, and study the encapsulation technology integrating local surface plasmon chip with microfluidic system; develop a highly sensitive and precise tumor marker imaging detection system that enables multi-channel parallel detection and identification of multiple tumor markers through imaging.
2. Requirements
The project must be led by an enterprise located in Guangdong Province. Joint research by enterprise-university-research institute consortium is encouraged.
3. Funding amount
The funding amount is capped at RMB 10 million.
Direction 2.15: Development of the fourth-generation nanopore sequencer and supporting pathogenic microorganism detection kits
1.Research content
Carry out the research and development of the four-generation nanopore integrated sequencing analysis system with automated extraction module, automated database construction module, nanopore sequencer module and data analysis module; study the quality control standards and relevant technologies, conduct pilot production in line with the technical specifications outlined by the National Medical Products Administration, and develop a proprietary fourth-generation nanopore sequencer and related supporting medical devices; develop pathogenic microorganism detection products, explore a detection method combining the sequence independent single primer amplification (SISPA) technology and the 16S ribosomal DNA and ITS sequence amplification technology against pathogenic bacteria, fungi and viruses, and develop stable, reliable, high-throughput, and low-cost pathogenic microorganism rapid detection kits; carry out research on the production process and quality system, pilot production, and product performance evaluation; establish a pathogenic microorganism detection technology platform, and put the developed equipment and products to clinical use.
2. Requirements
The project can be led by an enterprise or a public institution located in Guangdong Province. Joint research by enterprise-university-research institute consortium is encouraged.
3. Funding amount
The funding amount is capped at RMB 6 million.