Announcement on the Release of the 2024 National Natural Science Foundation of China Joint Fund for Regional Innovation and Development Project Guidelines (Second Batch)

Announcement on the Release of the 2024 National Natural Science Foundation of China
Joint Fund for Regional Innovation and Development Project Guidelines (Second Batch)

National Natural Science Foundation of China Regional Innovation Development in 2024

Joint Fund Project Guide (Second Batch)

　　The National Natural Science Foundation of China and local governments jointly funded the establishment of the Regional Innovation and Development Joint Fund, which aims to give full play to the guiding role of the National Natural Science Foundation, attract and gather superior scientific research forces across the country, and focus on major needs in regional economic and social development. Carry out basic research and applied basic research on key scientific issues, promote cross-regional and cross-department collaborative innovation, and promote the improvement of my country’s regional independent innovation capabilities.

　　The 2024 Regional Innovation and Development Joint Fund (second batch) will be funded in the form of key support projects. The funding period is 4 years, and the average funding intensity of direct costs is approximately 2.6 million yuan per project.

　　1. Biological and agricultural fields

　　(1) Based on the strategic needs of high-quality development in the biological and agricultural fields of Jiangsu Province, carry out relevant basic research around key scientific issues in the fields of synthetic biology regulatory mechanisms, endangered animal protection, crop molecular design breeding, prevention and control of livestock and poultry pathogen transmission, etc. or applied basic research.

　　Key support projects

　　research direction:

　　1. Research on the regulation mechanism of acidic polysaccharide biosynthesis and structural modification (for application code 1, select the subordinate code of C05)

　　Focusing on the major needs of the synthetic biology and life health industry in Jiangsu Province, carry out research on the biosynthesis of highly bioactive acidic polysaccharides such as heparin and chondroitin sulfate, elucidate the molecular weight distribution and regulatory mechanism of acidic polysaccharides, and reveal the structure-activity mechanism of key enzymes for sulfonation modification. Develop protein engineering methods to provide theoretical basis and scientific basis for efficient microbial synthesis of acidic polysaccharides.

　　2. Research on the microbial synthesis and regulatory mechanism of functional lipid chemicals (for application code 1, select the subordinate code of B08)

　　Focusing on the development needs of the health industry in Jiangsu Province, analyze the synthesis and distribution rules of oils and specific fatty acids of oil-producing microorganisms, explain the regulatory mechanism of lipid chemical synthesis, develop convenient and efficient genome editing technology of oil-producing microorganisms, and build a new generation of high-yield lipids The cell factory of chemicals provides theoretical basis and technical support for the synthesis of microbial lipid chemicals.

　　3. Discovery and utilization of excellent pear germplasm resources (for application code 1, select the subordinate code of C15)

　　In response to the problem of insufficient exploration and utilization of high-quality pear germplasm resources in my country, technologies such as whole-genome selection of pear and precise and efficient gene editing have been developed to discover and utilize key new genes with independent intellectual property rights to create high-quality, widely adaptable, stress-resistant, suitable and light-weight pear germplasm resources. New germplasm with simplified management and other traits were used to cultivate breakthrough new pear varieties and rootstocks.

　　4. Genetic mechanisms and design breeding of important traits of major field or horticultural crops (for application code 1, select the subordinate code of C13 or C15)

　　In view of the key bottlenecks faced by independent innovation in Jiangsu’s seed industry, the key genes that control disease resistance, high yield, high quality, ideal plant type and stress resistance of field or horticultural crops are excavated, the genetic and molecular mechanisms of the formation of excellent traits are clarified, and the key genes are explored based on New method of crop molecular design and breeding based on key gene editing to create excellent new germplasm.

　　5. Research on cross-species transmission mechanisms and new prevention and control technologies of important livestock and poultry pathogens (for application code 1, select the subordinate code of C18)

　　Aiming at the zoonotic pathogens that cause serious harm to the livestock and poultry breeding industry in Jiangsu Province, we will explore the variation, evolutionary adaptation and transmission paths of pathogenic bacteria among different hosts, and study the formation mechanism of drug resistance of pathogenic bacteria and their immune evasion strategies in different hosts. , to develop new prevention and control strategies and technologies for pathogenic bacteria based on Z bases, antimicrobial peptides, vaccine design or biological treatments.

　　6. Research on the Endangerment System and Protection Countermeasures of the Yangtze Finless Porpoise (for application code 1, select the subordinate code of C04)

　　Taking the Yangtze finless porpoise, an endangered flagship aquatic animal in the middle and lower reaches of the Yangtze River, as the research object, we systematically reveal the species evolution history and environmental adaptation strategies of the Yangtze finless porpoise, especially the population decline process and endangerment system under global environmental changes and human influence. In the context of the Yangtze River conservation This provides scientific basis and theoretical basis for the formulation of conservation and management strategies for the Yangtze finless porpoise.

　　Applicants for the above research directions are encouraged to apply in cooperation with universities, research institutions or enterprises in Jiangsu Province that have certain research strength and research conditions.

　　(2) Based on the development needs of life sciences in Jiangxi Province, carry out relevant basic research or applied basic research around key scientific issues in the fields of food science, developmental biology and other fields.

　　Key support projects

　　research direction:

　　1. Structural order and biosynthetic mechanism of active polysaccharides from medicinal and edible plants in the Poyang Lake Basin (for application code 1, select the subordinate code of C20)

　　Taking polysaccharide-rich medicinal and edible plants in the Poyang Lake Basin as the research object, we used genomics, metabolomics, chemometrics and other methods to conduct orderly assembly research on polysaccharide structures and reveal typical polysaccharide biosynthetic pathways and their regulation. mechanism, providing theoretical support for the efficient preparation of active polysaccharides.

　　2. Research on the medicinal ingredients and immune regulation of traditional Chinese medicine against ulcerative colitis (for application code 1, select the subordinate code of H32)

　　With the help of multidisciplinary technology, anti-ulcerative colitis medicinal ingredients are obtained from traditional Chinese medicines with proven clinical efficacy in clearing away heat and detoxifying. Combining the internal processes and their interaction with intestinal flora, the anti-inflammatory immune mechanism is elucidated and a suitable Drug delivery system.

　　3. Construction of human liver organoid models and research on disease mechanisms (for application code 1, select the subordinate code of C12)

　　Establish human organoid models of liver development, homeostasis and disease occurrence; analyze the molecular mechanisms of liver cell development, regeneration and disease; develop a new drug evaluation system using liver organoid disease models.

　　Applicants outside Jiangxi Province for the above research directions should apply in cooperation with universities, research institutions or enterprises in Jiangxi Province that have certain research capabilities and conditions.

　　(3) Based on the development needs of the agricultural and biological fields in Shaanxi Province, carry out basic research or applied basic research around key scientific issues such as the stress resistance and formation mechanisms of excellent traits of important grains, cash crops, and herbivorous livestock.

　　Key support projects

　　research direction:

　　1. Identification and utilization of genes regulating broad-spectrum resistance to major fungal diseases in wheat (for application code 1, select the subordinate code of C14)

　　Excavate wheat genes commonly used by stripe rust, Gibberella, powdery mildew, etc., clarify their contribution to resistance/susceptibility to various fungal diseases, reveal the common pathogenesis of different fungal diseases in wheat, and provide important targets for precise gene editing , providing a theoretical basis for provenance innovation.

　　2. Biological mechanism of efficient utilization of water and nitrogen in apple rootstocks under drought conditions (for application code 1, select the subordinate code of C15)

　　Focusing on the problem of soil moisture and nutrient deficiency in apple-producing areas on the Loess Plateau, we analyze the physiological basis and genetic characteristics of excellent apple rootstock resources for efficient water and nitrogen absorption and utilization under drought conditions, excavate key genes and create excellent new germplasm of dwarf rootstocks. Provide theoretical basis and new materials for efficient utilization of water and fertilizer in apples in arid areas.

　　3. Excavation of characteristic Qin medicine genetic resources and research on the formation mechanism of excellent traits (for application code 1, select the subordinate code of C02)

　　In order to solve the problems of unclear genetic background of Qin medicine and insufficient germplasm innovation, we collect and preserve germplasm resources such as jujube kernel and scutellaria baicalensis, explore key genes that affect the quality, yield, drought resistance and other target traits of medicinal materials, build a molecular regulatory network, and analyze excellent The molecular mechanism of trait formation, and the use of molecular design breeding technology to create new germplasm.

　　4. Research on the comprehensive regulation mechanism of genetic, nutritional and immune regulation of the number of lambs produced by Shaanbei white cashmere goats (for application code 1, select the subordinate code of C17)

　　In view of the low lambing rate and unclear regulation mechanism of lambing number of white cashmere goats in northern Shaanxi, the factors that regulate the lambing number of white cashmere goats were analyzed from the perspectives of genetics, nutrition, and immunity, and their regulatory mechanisms were clarified to construct white cashmere goat follicles. The development and ovulation control technology system provides a theoretical basis for the creation of white cashmere goat breeding sheep with high immunity and high lamb production.

　　The above research directions encourage applicants to conduct cooperative research with universities, research institutions or enterprises with certain research strength and research conditions in Shaanxi Province.

　　2. Environment and ecological fields

　　(1) Based on the major needs of ecological and environmental protection in Jiangsu Province, carry out relevant basic research or applied basic research around key scientific issues in the fields of carbon neutral cutting-edge technology, environmental pollution control, ecological hydrology and water resources.

　　Key support projects

　　research direction:

　　1. Creation of prebiotics derived from straw and the biological mechanism of regulating the soil rhizosphere (for application code 1, select the subordinate code of D07)

　　Aiming at the key technical issues of straw resource utilization and soil improvement, discover and transform straw-decomposing multifunctional enzyme systems and enzyme-producing chassis cells, elucidate the mechanism of enzyme systems to efficiently decompose lignocellulose and directional release of functional substances, and develop low-carbon straw-derived prebiotics. The preparation process reveals the biological mechanism by which prebiotics regulate rhizosphere microflora succession and promote plant growth.

　　2. Generation mechanism and control strategy of secondary fine particles from heavy haze pollution (for application code 1, select the subordinate code of B06)

　　Focusing on the key scientific issues of the causes and prevention of heavy haze pollution in typical areas, we integrate multi-scale and multi-scenario field observations, inorganic/organic full chemical component analysis and numerical simulations to reveal the characteristics of atmospheric particulate matter, especially secondary fine particles, under real heavy haze conditions. Form a mechanism to clarify the nonlinear response rules between emissions, meteorology and secondary pollution, and propose efficient prevention and control strategies for regional heavy haze pollution.

　　3. Lake carbon sink fishery process and regulatory mechanism under the background of fishing ban (for application code 1, select the subordinate code of C03)

　　Aiming at the key scientific issues of carbon sequestration and fishery under the background of lake fishing ban, we study the characteristics and potential of fishery carbon sequestration in typical lake ecosystems in Jiangsu Province, clarify the ecosystem carbon sequestration process driven by the evolution of fishery resources, and reveal the impact of fishing ban on lake carbon sequestration efficiency. and regulatory mechanisms, and proposed a carbon sink fishery expansion approach based on the carrying capacity of resources and the environment.

　　4. Research on plant joint remediation and high-value utilization mechanism of heavy metal contaminated soil (for application code 1, select the subordinate code of D07)

　　Aiming at the key scientific issues of screening and high-value utilization of soil remediation plants for heavy metal pollution, we conducted research on the efficient joint remediation and high-value utilization mechanism of horticultural plants and heavy metal hyperaccumulator plants, assessed the soil environmental risks of plant joint remediation, and clarified the safety of horticultural plants in heavy metal-contaminated soil. Physiological and molecular mechanisms of efficient enrichment in production and hyperaccumulator plants.

　　5. Research on large models of artificial intelligence weather forecasting (for application code 1, select the subordinate code of D05)

　　Aiming at the key scientific issues in refined weather forecasting, develop key technologies for artificial intelligence weather forecasting large models, construct weather system neural network forecasting models based on meteorological physics constraints, and study super-resolution physical process interpretation methods and multi-dimensional spreadsheets for key meteorological elements. Mass parallel computing technology is used to improve the forecast accuracy and operating efficiency of weather forecast models.

　　6. Research on intelligent sensing and assimilation accounting of carbon budget with kilometer-level resolution (for application code 1, select the subordinate code of D01 or D05)

　　Based on the scientific and technological needs of precise carbon assimilation inversion systems for precise accounting of greenhouse gases, develop high-precision intelligent sensing technology for CO ₂ and CH ₄ concentration star-space-ground integration, build a collective assimilation method for CO ₂ and CH ₄ multi-source observation data, and develop The kilometer-level resolution carbon budget assimilation accounting system and its theoretical system provide support for refined accounting of greenhouse gas emissions and optimization of carbon neutral paths.

　　7. The relationship and mechanism between rice phenotype and methane emissions from rice fields (for application code 1, select the subordinate code of C13)

　　Aiming at the key scientific issues of the synergy between high rice yield and carbon emission reduction, identify low methane emission rice varieties under high yield management level, clarify the key phenotypes of low methane emission rice, explore its relationship with methane emissions in rice fields, and reveal the synergy of high yield and emission reduction. The “crop-microorganism” interaction mechanism provides scientific basis for the breeding of high-yielding and water-reducing rice varieties and the innovation of rice technology.

　　8. Creation and mechanism of action of new radiation protection drugs for nuclear emergency medical treatment (for application code 1, select the subordinate code of B06)

　　In response to the scientific and technological needs of radiation damage protection under different nuclear irradiation conditions, establish a new method for screening and designing protective drugs based on key damage mechanisms, develop new multi-target drugs that can prevent and treat radiation damage, and clarify the functions of different radiation protection groups in drugs. The synergistic mechanism provides a basis for the development of a series of new radiation protection drugs.

　　9. Research on the stability of lake ecosystems and biodiversity maintenance mechanisms on the eastern route of the South-to-North Water Diversion Project (for application code 1, select the subordinate code of D07 or D01)

　　In view of the current ecological and environmental problems of lakes in Jiangsu on the eastern route of the South-to-North Water Diversion Project, we will conduct research on the long-term evolution patterns, mutation processes and driving mechanisms of typical lake ecosystems, reveal their stability and biodiversity maintenance mechanisms, and clarify the impact of extreme climate events and cross-basin water diversion on lakes. The impact on ecological security and strategies to improve lake ecosystem functions and biodiversity are proposed.

　　10. Research on new technologies and principles of low-carbon treatment of lithium battery wastewater (for application code 1, select the subordinate code of E10)

　　In view of the complex state of metal ions in lithium battery production wastewater and the difficulty in regulating the bioconversion pathways of refractory organic nitrogen, develop key metal ion interface targeted recovery principles and new methods, establish bioconversion control technology of refractory organic nitrogen, and develop lithium batteries The new low-carbon and efficient wastewater treatment process provides scientific and technological support for the development of the lithium battery industry.

　　11. Change characteristics and simulation predictions of coastal wetland carbon sinks (for application code 1, select D07 or a subordinate code of D01)

　　In view of the unclear carbon sink characteristics and unclear formation mechanisms of Jiangsu coastal wetland ecosystems, the spatiotemporal dynamic characteristics and driving mechanisms of carbon storage and carbon flux in coastal wetlands under the influence of climate change and human activities were studied to reveal the key formation processes of carbon sinks and their Regulatory mechanism, build a quantitative assessment model for carbon sequestration and sink increase, and predict the sink increase potential of coastal wetland ecosystems under climate change.

　　Applicants for the above research directions are encouraged to conduct cooperative research with universities, research institutions or enterprises in Jiangsu Province that have certain research strength and research conditions.

　　(2) Carry out basic research or applied basic research around the major needs of ecological environment protection and social development in Shaanxi Province, focusing on key scientific issues such as ecological environment restoration, sustainable utilization of mineral resources, and prevention and control of collapsible loess disasters.

　　Key support projects

　　research direction:

　　1. The mutual feedback mechanism between vegetation restoration and soil hydrological processes on the Loess Plateau (for application code 1, select the subordinate code of D07)

　　In view of the unclear relationship between vegetation greening and soil hydrological processes in the Loess Plateau, we studied the distribution characteristics of deep soil moisture at the regional scale in the Loess Plateau, revealed the dynamic mutual feedback mechanism between vegetation restoration and deep soil moisture, and elucidated the key layers of soil moisture changes under different degrees of greening. and flux, and proposed artificial regulation strategies for vegetation restoration and soil water resources adaptation pattern in the Loess Plateau.

　　2. Evolution and restoration mechanism of ecological hydrological system under high-intensity coal mining in Mu Us Sandy Land (for application code 1, select the subordinate code of E09)

　　In view of the key scientific issues of the impact of high-intensity coal mining on the evolution and restoration of ecological and hydrological systems in the Mu Us Sandy Land, the migration and transformation processes of surface water, vadose zone water and groundwater were studied, the characteristics of ecosystem mining loss and the evolution mechanism of carrying capacity were clarified, and the post-mining mining areas were elucidated. Ecological and hydrological system interaction mechanisms and restoration thresholds, and the development of ecological and hydrological coupling restoration theory in underground and open-pit mining areas.

　　3. Microbial effects and resource effects during the formation of black shale in southern Shaanxi (for application code 1, select the subordinate code of D02)

　　In view of the unclear relationship between the geological microbial effects during the formation of the Neoproterozoic to Cambrian black shale in southern Shaanxi and the mineral resource enrichment mechanism, the microbial types and geological effects during the formation of the black shale were clarified and analyzed. Microbial sedimentation, diagenesis, mineralization, accumulation mechanisms and resource effects in black shale.

　　4. Multi-physics effects and reinforcement repair mechanism of microwave sintering of collapsible loess (for application code 1, select the subordinate code of F01)

　　In view of the key scientific issues in the sintering method of collapsible loess, the high-power microwave sintering reinforcement method of collapsible loess is studied, a multi-physics field effect simulation method of the loess sintering process is established, and the interaction mechanism between collapsible loess and microwave is revealed. Carry out research on the development, test verification and monitoring of microwave sintering equipment to provide a new green and environmentally friendly method for collapsible loess sintering.

　　5. Carbon emission mechanism and emission reduction principle during sewage collection and transportation in the Guanzhong Plain area (for application code 1, select the subordinate code of E10)

　　Focusing on the key scientific issues of carbon emissions from the urban sewage pipe network in the Guanzhong Plain, clarify the occurrence characteristics and phase transformation and migration rules of carbon pollutants in the sewage collection and transportation process, clarify the carbon emission forms and critical paths of the sewage pipe network system, and establish a carbon emission accounting method , put forward the theory of phase stability control of carbon pollutants, and provided technical support for the low-carbon operation of the sewage collection and transportation system in the Guanzhong Plain area.

　　The above research directions encourage applicants to conduct cooperative research with universities, research institutions or enterprises with certain research strength and research conditions in Shaanxi Province.

　　3. Energy and chemical industry

　　(1) Carry out relevant basic research or applied basic research around Jiangsu Province’s development needs in the fields of clean energy and green chemicals, and around key scientific issues in clean energy conversion and utilization, efficient energy storage technology, smart grids and other fields.

　　Key support projects

　　research direction:

　　1. Research on new wide bandgap inorganic and organic-inorganic hybrid thin film photovoltaic cells (for application code 1, select the subordinate code of B09)

　　In view of the difficulty in balancing the optical and electrical properties of the interconnection layer in existing crystalline silicon laminated photovoltaic cells, research on inorganic and organic-inorganic hybrid wide bandgap thin film photovoltaic devices optically coupled with crystalline silicon is carried out, and large-area high-performance thin film preparation technologies are explored. Develop interface modification strategies to reveal the transmission and recombination mechanisms and control principles of photogenerated carriers in stacked photovoltaic devices, providing theoretical support for further improving the efficiency and reducing costs of photovoltaic cells.

　　2. Research on the mechanism and system design method of high-density fast-response heat and hydrogen storage (for application code 1, select the subordinate code of E06)

　　Facing the major demands for efficient energy utilization and low-carbon transformation, and focusing on the key scientific issues of the heat storage and hydrogen storage mechanism, we construct high enthalpy and high thermal conductivity composite phase change materials, and elucidate the cross-scale multi-interface heat and mass transfer mechanism and the evolution of the solid-liquid phase change process. According to the laws, a design method for constructing a high-density and fast-response phase change heat storage and hydrogen storage system can be achieved to achieve synergy between high-temperature phase change heat storage and solid-state thermochemical hydrogen storage.

　　3. Research on electrode interface stability and synergistic structure-activity mechanism of high specific energy power batteries (for application code 1, select the subordinate code of B02)

　　To meet the needs of high specific energy power batteries such as safety and environmental adaptability, we focus on the research on the stability of the battery electrode interface, build a dynamic model of the electrode interface, analyze the failure mechanism of power batteries under high and low temperature conditions, and clarify the synergistic structure-activity relationship between the interface and battery performance. , providing scientific support for the research and development of next-generation high-specific-energy batteries.

　　4. Research on the evolution and dynamic reconstruction of the electrochemical microinterface of high-security energy storage batteries (for application code 1, select the subordinate code of E02)

　　Design functional electrode material microinterfaces, develop new methods for in-situ electrochemical interface evolution, explore the correlation mechanism between microinterface structural deterioration and battery performance failure, elucidate the dynamic evolution mechanism of multi-component microinterfaces, and achieve in-situ dynamic reversible reconstruction of microinterfaces , reveal the influence of dynamic micro-interface multi-factor coupling on its electrochemical performance, and build a high-safety energy storage battery system suitable for deep water, high altitude, high and low temperature and other multi-domain applications.

　　5. Research on the design and preparation of high-temperature membrane materials and electrodes (for application code 1, select the subordinate code of B08)

　　Focusing on direct ammonia fuel cell ceramic proton conductor electrolyte membranes and air/hydrogen electrode materials, we study membrane materials and electrode structures with high electrochemical activity and high temperature thermal stability, clarify the interface coupling mechanism between electrodes and electrolyte membranes, and reveal the actual work The attenuation mechanism of membrane electrode materials under normal conditions.

　　6. Research on green preparation and separation mechanism of biomedical separation membrane materials (for application code 1, select the subordinate code of B08)

　　To meet the needs of precise separation of active substances in the biomedical industry, develop high-performance nanofiltration membrane materials based on natural products as monomers, develop new methods for precise control of nanofiltration membrane microstructure, explore the mass transfer mechanism of ions and key active components, and achieve key goals. The efficient separation of active components lays a theoretical foundation for the localization of biomedical separation membranes.

　　7. CO ₂ efficient separation and capture materials and external field strengthening mechanism (for application code 1, select the subordinate code of B08)

　　In response to the demand for efficient CO ₂ separation, develop new functional materials with external field-responsive adsorption (absorption), reveal the material structure-activity relationship and the external field-enhanced separation mechanism, and elucidate the regulation mechanism of external fields on material properties and separation performance, providing a basis for the development of high-efficiency and low-energy CO ₂ capture Provide theoretical support for integrating separation techniques and processes.

　　8. Research on the construction and application of cluster assembly catalysts (for application code 1, select the subordinate code of B01 or B02)

　　Focusing on the problem of precise synthesis of isocyanate monomer materials through carbonylation reaction, we use the intrinsic activity of the core of atomic clusters and use its ligands as peripheral structures to construct catalytic materials with homogeneous heterogeneous properties, revealing the synergistic catalysis between the core and peripheral structures. The new mechanism achieves simultaneous improvement in conversion rate and selectivity, providing a scientific basis for the synthesis of high-end polyurethane material monomers.

　　9. Research on the operation stability and control strategy of gravity compressed air energy storage (for application code 1, select the subordinate code of E08)

　　In view of the operation control problems of the new gravity compressed air energy storage device, the “gas-solid-film” dynamic coupling behavior of the sealing film and the gravity block under the action of high-pressure gas is studied, the critical instability mechanism of the attitude tilt of the gravity block is explored, and safe and stable operation control technology is developed.

　　10. Research on high-performance catalytic membrane materials and membrane reactors (for application code 1, select the subordinate code of B08)

　　In response to the application needs of catalytic membrane reactors, a method for controlling the surface properties of multi-channel ceramic membranes was developed to clarify the distribution and control mechanism of active components on the membrane, and to reveal the rules for the amplification and preparation of catalytic membranes. Construct a catalytic membrane reactor, study the coupling rules of the membrane separation process and the catalytic reaction process, and develop the catalytic membrane reactor strengthening theory.

　　Applicants for the above research directions are encouraged to apply in cooperation with universities, research institutions or enterprises in Jiangsu Province that have certain research strength and research conditions.

　　(2) Focusing on the development needs of the energy and chemical industry in Jiangxi Province, carry out relevant basic research or applied basic research on major scientific issues in the fields of mining and metallurgical engineering, metal energy, environmental engineering and other fields.

　　Key support projects

　　research direction:

　　1. Research on the new mechanism of selective resource conversion and volume reduction and solidification of solid waste/waste liquid (for application code 1, select the subordinate code of E10)

　　Facing the demand for resource utilization of heavy metals in typical solid waste/waste liquid, explore the extreme migration of heavy metals in environmental media, selective resource conversion, and new mechanisms of volume reduction and solidification of radioactive organic waste liquids, and study selective adsorption-resource conversion-volume reduction and solidification. new materials, methods and processes.

　　2. Research on liquid flow control and resource utilization mechanism in ion adsorption rare earth leaching process (for application code 1, select the subordinate code of E04)

　　In view of the low efficiency and environmental pollution problems in the ionic rare earth leaching and smelting chemical separation process, we conduct research on the mineralogy characteristics and pore evolution rules of ore bodies, reveal the green leaching mechanism based on liquid flow permeability control and resource recycling, and develop green Low-carbon valuable element recycling and pollution control technology.

　　3. Research on high-capacity, long-life rare earth alloy hydrogen storage materials and hydrogen absorption and release mechanisms (for application code 1, select the subordinate code of E01)

　　In order to solve the problems of limited hydrogen storage capacity and low cycle life of solid alloy materials, develop rare earth alloy hydrogen storage materials with high capacity and long cycle life, study the chemical forms and distribution of different rare earth elements in alloy materials, and reveal their effect on hydrogen absorption and release of materials. Efficiency influence law and mechanism of action to construct a new high-capacity, long-life rare earth alloy hydrogen storage system.

　　4. Preparation of thermoelectric materials for radioisotope thermoelectric power generation and research on device service performance (for application code 1, select the subordinate code of E02)

　　Aiming at the problem of low thermoelectric conversion efficiency of radioisotope batteries, design and prepare new high-performance thermoelectric materials, develop new thermoelectric devices, reveal the evolution and attenuation mechanism of the interface layer of thermoelectric materials at high temperatures, build high-performance principle prototypes, and study the service performance of thermoelectric devices. .

　　5. Research on the design and synthesis of nucleotide antiviral drugs (for application code 1, select the subordinate code of B01)

　　Facing the precise synthesis of nucleotide antiviral drug molecules, aiming at the cross-disciplinary frontier of “organic chemistry + computational chemistry”, taking complexly substituted nucleoside antiviral drug molecules as the synthesis object, and conducting systematic research around reaction design, mechanism and applicability , providing a new method for the catalytic synthesis of nucleotide drugs.

　　Applicants outside Jiangxi Province for the above research directions should apply in cooperation with universities, research institutions or enterprises in Jiangxi Province that have certain research capabilities and conditions.

　　(3) Carry out basic research or applied basic research around the industrial upgrading and technological updating of Shaanxi’s energy and chemical industry, focusing on key scientific issues in the directions of deep energy mining, renewable energy utilization, and development of high-value chemical products.

　　Key support projects

　　research direction:

　　1. Research on laser spectroscopy detection methods of mineral elements and organic components in unconventional reservoir rocks (for application code 1, select the subordinate code of E07)

　　To meet the needs of exploration and development of unconventional fossil resources such as shale oil and gas, study the laser action mechanism, spectral control enhancement method and quantitative measurement algorithm of laser-induced breakdown spectrum under complex rock matrix, develop detection methods and devices for multi-laser spectrum fusion, and realize rock Rapid detection of mineral element content and organic matter characteristics.

　　2. Research on intelligent prediction of typical disaster risks of coal mine fire and gas (for application code 1, select the subordinate code of E04)

　　In order to solve the problem of difficult identification of multiple hidden disaster factors in coal mines, we study the multi-factor coupling disaster mechanism of typical coal mine fire and gas disasters, establish an artificial intelligence prediction model of typical coal mine disaster risks, and mine the origin of hidden risks based on monitoring data to realize the mining process. Early warning and precise prevention of medium- to high-disaster risks.

　　3. Research on ultra-low temperature supercapacitors based on biomass and chemical solid waste (for application code 1, select the subordinate code of B08)

　　In response to the low cost and extreme cold resistance requirements of large-scale energy storage, develop high-efficiency carbon-based composite electrode materials using biomass and chemical solid waste as raw materials, prepare ultra-low temperature and high-voltage electrolytes, and reveal the coupling rules and interfaces between electrodes and electrolytes. The energy storage mechanism of electrochemical reactions is used to develop ultra-low temperature (below minus 70°C) high-performance supercapacitors.

　　4. Research on the selective production of aromatics from coal tar through medium-low temperature pyrolysis of oil-rich coal (for application code 1, select the subordinate code of B08)

　　Facing the major demand for high-value utilization of coal tar from low-temperature pyrolysis of oil-rich coal, research new methods of coal tar separation and catalytic conversion to produce aromatic hydrocarbons, reveal the separation mechanism and transformation rules of different components of coal tar, and provide high selectivity for coal tar. New technologies for producing aromatics provide a theoretical basis.

　　5. Research on the design method system of solar zero-carbon heating for urban buildings (for application code 1, select the subordinate code of E08)

　　Based on the regional climate, solar energy endowment and urban building characteristics of the Loess Plateau, the principle of differentiated and efficient thermal insulation design of buildings is proposed, the time-sharing zoning heating heat demand law and load calculation method are studied, and the coordination of multiple solar heat sources, on-demand heat storage and pipe network width are clarified It will establish a precise transmission and distribution mechanism, build an all-solar heating design method system, and provide a theoretical basis for realizing zero-carbon heating of urban buildings.

　　6. Research on high-precision positioning and environmental reconstruction methods of unmanned excavation equipment in deep mining areas (for application code 1, select the subordinate code of F05 or F03)

　　To meet the demand for intelligent development of unmanned excavation equipment in mining areas, explore the high-precision parallel positioning mechanism of multiple measurement points in the light field in the excavation environment, clarify the independent positioning mechanism of multi-modal information coupling, study the real-time construction theory of tunnel digital models, and propose unmanned excavation equipment. Autonomous sensing and reliable positioning methods provide scientific support for the development of high-end equipment.

　　7. Research on hydrogen-carbon co-generation of organic solid waste in energy and chemical industry (for application code 1, select the subordinate code of B08 or B06)

　　In response to the demand for efficient utilization of organic solid waste from energy and chemical industries such as oily sludge and tar residue, design and prepare pyrolysis/reforming coupling catalysts, reveal the influence of catalyst structure and coupling method on hydrogen-carbon cogeneration of organic solid waste, and clarify the reaction mechanism. , providing a theoretical basis for the efficient utilization of organic solid waste.

　　The above research directions encourage applicants to conduct cooperative research with universities, research institutions or enterprises with certain research strength and research conditions in Shaanxi Province.

　　4. New materials and advanced manufacturing fields

　　(1) In response to the development needs of Jiangsu Province in the field of new materials and advanced manufacturing, carry out relevant basic research or applied basic research around key scientific issues in the fields of design and preparation of new materials, micro-nano and precision manufacturing.

　　Key support projects

　　research direction:

　　1. Atomic-level manufacturing of molecular quantum materials (for application code 1, select the subordinate code of B02)

　　Develop surface-in-situ synthesis methods with atomic precision, accurately prepare new molecular quantum materials such as organic molecular magnets, organic topological materials, and organic open-shell materials, and use in-situ, multi-physical property characterization technology based on scanning probe microscopy to realize molecular quantum materials Atomic-level characterization of basic physical properties such as geometric structure, composition, valence state, spin, and electronic structure, and the establishment of cross-scale models of basic physical properties and device performance to provide theoretical foundations and technical support for the development of new molecular quantum devices.

　　2. Atomic manufacturing of carbon-based cluster electronic devices (for application code 1, select the subordinate code of A21)

　　In response to the major demand for the next generation of new micro-nano electronic device primitives and functional integration, multi-field responsive carbon-based clusters are prepared, their response characteristics under various external fields are controlled, and their response mechanisms under external fields are revealed, and further Using carbon-based clusters as basic elements, we can develop carbon-based electronic devices with extreme micro-nano dimensions and realize functions such as information storage, computing, and sensing.

　　3. Precise construction and control of low-dimensional bipolar transition metal-based n/p-type semiconductor materials and interfaces (for application code 1, select the subordinate code of F04)

　　Focusing on the demand for semiconductor materials for integrated circuits in the post-Moore era, we design and accurately prepare low-dimensional n-type and p-type transition metal compound semiconductor wafers, explore the dynamic process of controllable growth of large-area, low-defect density materials, and propose the construction of orderly The atomic manufacturing strategy of mesoscopic nanostructures reveals its influence and regulation mechanism on carrier transport, providing a new material basis and technical approach for integrated circuits in the post-Moore era.

　　4. Preparation of low-dimensional transition metal oxides and their associated quantum state control (for application code 1, select the subordinate code of A20)

　　Focusing on basic scientific issues such as the novel correlated quantum states of new low-dimensional transition metal oxides and their regulation, develop oxide epitaxial thin film growth, peeling and precise transfer technologies that are precisely controllable at the atomic scale, and prepare high-quality oxide self-supporting artificial microstructures , study the regulation of its physical properties and associated quantum states by factors such as strain (gradient), dimension and interface, and reveal new rules for its physical state regulation.

　　5. Basic research on new multifunctional materials and devices based on ferroelectric nanotopology and metasurfaces (for application code 1, select the subordinate code of A20)

　　In response to the urgent needs for high integration, low energy consumption, and high efficiency of material detection and information storage devices, develop precise preparation technology for ferroelectric nanotopological structures, optimize the design, processing integration, and special calibration solutions of cascade metasurfaces, and develop based on New multifunctional materials with ferroelectric nanotopological structures and metasurfaces reveal the rules and mechanisms of controlling their physical properties by external fields such as electricity, force, light, and heat, and develop new devices for storage, detection, and sensing based on this material.

　　6. The physical state basis and molecular control mechanism of highly stable destructurable polymers (for application code 1, select the subordinate code of B05)

　　Focusing on the key issues of the synergistic mechanism between functional groups and network order of deformable polymer materials, we conduct research on the physical state control and structure-activity relationship of polymer materials, explore the influence of molecular engineering and physical state control on material performance and stability, and clarify the influence of molecular engineering and physical state control on material performance and stability. The coupling mechanism with polymer processing technology provides theoretical basis and technical support for the large-scale manufacturing and application of high-performance deformable polymer materials.

　　7. Multi-scale mechanics and intelligent design of cement-based composite metamaterials (for application code 1, select the subordinate code of E02 or E08)

　　Focusing on the significant demand for strategic structural materials for sustainable economic development and high performance, carry out research on the composite of negative Poisson’s ratio metamaterials and cement-based materials, study the multi-scale mechanical constitutive relationship of cement-based composite metamaterials, and reveal the cement-based composite The impact mechanism of multi-scale structure of metamaterials on modulus, strength and toughness is proposed. An intelligent design method for cement-based composite metamaterials is proposed to construct a high-throughput database of cement-based composite metamaterials to achieve cement with the goals of synergistic improvement of strength and toughness and economic optimization. Reverse design of matrix composite metamaterial structures.

　　8. Research on the construction and regulation mechanism of plasmonic photocatalytic materials with spatial separation characteristics (for application code 1, select the subordinate code of B05)

　　By designing and accurately constructing plasmonic photocatalysts with spatial separation characteristics, we explore the hot electron injection and hot carrier generation and transport behaviors during the plasmon photocatalysis process, and reveal their spatial separation characteristics and regulatory mechanisms. Develop new methods for solar-driven carbon dioxide reduction, expand the application of plasmonic nanomaterials in the field of solar energy conversion, and provide new development pathways for achieving carbon neutrality.

　　9. Research on the preparation and mechanism of action of new near-infrared photodynamic therapy photosensitizers (for application code 1, select E03 or the subordinate code of E13)

　　Focusing on the key issues in the application of photosensitizers in photodynamic therapy, develop the design theory and technology of high-efficiency near-infrared photosensitizers, explore the key factors affecting the excited state energy release of photosensitizers, and study the structure, excited state behavior and high reactive oxygen species generation capacity of photosensitizers. The inherent laws and control technology between them have achieved breakthroughs in the diagnostic and therapeutic performance of near-infrared photosensitizers, providing a technical foundation for efficient photodynamic therapy.

　　10. Theoretical research on multi-energy field-assisted three-dimensional bending and torsion precision forming of titanium alloy components (for application code 1, select the subordinate code of E05)

　　In response to the demand for high-precision integrated manufacturing of three-dimensional bending and torsion components of titanium alloy profiles with high performance and complex cross-sections for aerospace applications, research on the multi-energy field bending and torsion forming mechanism and macro-micro modeling of titanium alloy profiles was carried out to reveal irregular profiles under the action of multi-energy fields. Differential response mechanisms between cross-section and bending-torsion rebound, develop microstructure evolution and plastic instability prediction methods in the multi-energy field bending and torsion forming process, establish complex axis formation and multi-parameter collaborative precision control models, and provide bending and torsion solutions for titanium alloy profiles with complex cross-sections Provide theoretical basis and technical support for high-quality and efficient forming of components.

　　11. Basic research on pulse dynamic electrolysis compound milling (for application code 1, select the subordinate code of E05)

　　Aiming at the manufacturing challenges of weak-stiffness structures in aerospace, we study the basic theory and key technologies of pulse dynamic electrolysis composite milling, reveal the reliable generation mechanism of energy pulse dynamics and the rules of composite machining, and break through the optimization of energy flow/material flow pulse dynamic coupling and rapid product delivery. Key technologies such as precise transportation control provide support for high-performance manufacturing of key aerospace components.

　　12. Theory and method of in-situ measurement of multi-dimensional residual stress field of large components (for application code 1, select the subordinate code of E05)

　　In response to the urgent need for in-situ measurement of multi-dimensional residual stress fields of large components, we should explore the equivalence principle of multi-directional deformation forces and residual stress fields on component deformation, reveal the multi-scale representation mechanism of deformation forces on residual stress fields, and establish a fusion of deformation force data and Physics knowledge reconstructs the neural operator model of the residual stress field to achieve multi-dimensional and accurate in-situ measurement of the residual stress field of large components.

　　13. Research on digital-analog hybrid control method of high-dimensional electro-hydraulic driven Euler-Lagrangian system (for application code 1, select the subordinate code of E05)

　　In view of the complex dynamics of high-dimensional Euler-Lagrangian systems and the difficulty of high-performance control of electro-hydraulic heavy loads, we studied the coupling mechanism of mechanical-electro-hydraulic dynamics, constructed a complex system dynamic model paradigm, and proposed electro-hydraulic drive High-performance digital-analog hybrid intelligent control method, and its application is verified on articulated industrial robots with more than six degrees of freedom.

　　14. Research on organic semiconductor single crystal field effect transistor materials and integrated devices for intrinsically flexible display driving (for application code 1, select the subordinate code of E03)

　　In response to the demand for intrinsically flexible driving of organic semiconductor single crystal field effect transistors in next-generation display technology, and focusing on key scientific issues in large-area preparation, performance control, and device integration of organic semiconductor single crystal materials, high-mobility organic semiconductor single crystal fields are developed. Effect transistor integrated devices, breaking through the key technologies of organic semiconductor single crystal field effect transistor display driving, laying the foundation for building organic intrinsically flexible display devices.

　　15. Construction and control mechanism of efficient flexible optical devices (for application code 1, select the subordinate code of B05)

　　Facing the demand for efficient flexible molecular devices for micro-robots, with the efficient conversion of light energy to mechanical energy as the core, and based on the design and preparation of new flexible molecular materials, we will conduct in-depth development of the design and preparation of photosensitive coordination polymer materials and organic semiconductor luminescent materials. and structure-activity relationship research, develop new methods for constructing efficient flexible optical devices, break through key technologies such as energy conversion, photo-induced deformation, and photoelectric control, laying the foundation for the application of efficient flexible optical devices in the field of microrobotics.

　　16. Research on lunar-based equipment body-foot system-lunar soil coupling dynamics and safe transportation (for application code 1, select the subordinate code of E05 or E08)

　　In view of the scientific issue of the lunar-based equipment body-foot system-lunar soil coupling during the construction of the lunar scientific research station, the lunar-based equipment body-foot system-lunar soil contact mechanism is explored, and the lunar-based equipment body-foot system-lunar soil coupling dynamics are established. The model reveals the influence of lunar appearance and lunar soil on the operation and transportation of lunar-based equipment, and provides theoretical support for the precise operation and safe transportation of lunar-based equipment.

　　17. Research on active enhanced sensing and collaborative control methods for electric heavy truck wire-controlled chassis (for application code 1, select the subordinate code of E12)

　　In response to the collaborative control requirements of wire-controlled chassis for autonomous electric heavy-duty trucks, the multi-vector dynamics coupling model and active enhanced sensing method of wire-controlled chassis are studied, the control mechanism of electro-hydraulic composite steering force and displacement synergy, and multi-electric braking dynamic synergy are revealed, and a line-by-wire chassis dynamic synergy control mechanism is proposed. Control-chassis collaborative control and vehicle-road-cloud collaborative autonomous evolution control methods provide theoretical and technical support for the development of high-level autonomous driving.

　　18. Basic research on the application of distributed drive hub motor systems (for application code 1, select the subordinate code of E07)

　　In view of the harsh working environment, difficult heat dissipation, and high impact resistance requirements of the distributed drive wheel hub motor system, the multi-physics coupling mechanism of the wheel hub motor’s electricity, magnetism, heat, force, and flow was studied, and a collaborative optimization design method for the motor system was proposed to break through complex working conditions. The key technologies for efficient heat dissipation and high-reliability sealing of motors under certain conditions provide theoretical foundation and technical support for the industrialization of distributed drive hub motor systems.

　　19. Cross-scale design and preparation of ceramic matrix composite structures for aeroengines (for application code 1, select the subordinate code of E02)

　　In order to realize the fine structural design and controllable preparation of continuous fiber-reinforced ceramic matrix composites for aero-engines, research on micro-design and macro-construction methods, establish integrated integration technology of prefabricated body weaving and sintering densification processes, and develop high-strength composite material structures New control methods and new preparation technologies promote the application of ceramic matrix composite materials in my country’s advanced aerospace engines.

　　Applicants for the above research directions are encouraged to apply in cooperation with universities, research institutions or enterprises in Jiangsu Province that have certain research strength and research conditions.

　　(2) Based on the development needs of Jiangxi Province’s new materials and advanced manufacturing fields, carry out relevant basic research or applied basic research around key scientific issues in the fields of new material design and preparation, and mechanical design and manufacturing.

　　Key support projects

　　research direction:

　　1. Design, synthesis and performance research of two-dimensional molecular ferroelectric materials (for application code 1, select the subordinate code of B05)

　　In response to the needs of miniaturization, thinness, and integration of electronic devices, develop the design and preparation technology of two-dimensional molecular ferroelectric materials, study the assembly and film construction rules of two-dimensional molecular ferroelectric materials, and reveal the structure-activity relationship between their structure and performance. , laying the foundation for the application of ultra-thin two-dimensional molecular ferroelectric films.

　　2. Basic research on the green preparation and application of wear-resistant and corrosion-resistant coatings for the aviation industry (for application code 1, select the subordinate code of E01)

　　In response to the aviation industry’s urgent need to replace electroplated hard chromium, a new wear-resistant and corrosion-resistant coating system and its advanced and environmentally friendly remanufacturing technology are developed to reveal the relationship between coating composition, structure, manufacturing process and performance, and provide a new alternative to traditional hard chromium plating. Laying the foundation for coating upgrades and replacements.

　　3. Research on the MOCVD epitaxial growth mechanism and preparation of yttrium barium copper oxide high-temperature superconducting strips (for application code 1, select the subordinate code of E02)

　　Facing the potential application of yttrium barium copper oxide high-temperature superconducting strips in important fields such as high current transmission and strong magnetic fields in the future, it is useful to study the dynamics of high crystallinity of rare earth ions in the oxygen atmosphere during strip growth and the microstructure of yttrium barium copper oxide. ordering mechanism, establish its physical relationship with critical current density, and promote the development of MOCVD preparation technology for rare earth high-temperature superconducting strips.

　　4. Electromagnetic loss mechanism and wave absorption performance control of rare earth doped magnetically modified ceramics (for application code 1, select the subordinate code of E01)

　　Aiming at the demand for special ceramic materials for absorbing stealth under high-temperature and broadband conditions, we conduct research on frequency band regulation of rare earth-doped magnetically modified ceramic coatings, elucidate the evolution of magnetic domains under the coupling effect of thermal fields and electromagnetic fields, and reveal electromagnetic losses under multiple physical fields. Microscopic mechanism, and a high-temperature wave-absorbing stealth control strategy is proposed.

　　5. Basic research on fine manufacturing of 3D printed regenerative tissues (for application code 1, select the subordinate code of E05)

　　In order to solve the problem of preparing biopolymer spherical powder for laser 3D printing, we study the spheroidization and shaping mechanism of irregular powder under coupled external fields, develop the preparation technology of biopolymer spherical powder, and explore the controllable manufacturing technology of regenerative tissue fine structure and its basic theory.

　　Applicants outside Jiangxi Province for the above research directions should apply in cooperation with universities, research institutions or enterprises in Jiangxi Province that have certain research capabilities and conditions.

　　(3) Based on the major needs for the high-quality development of new materials and advanced manufacturing in Shaanxi Province, focus on key scientific issues in the design and efficient preparation of new materials, and high-performance manufacturing of complex structures, and carry out basic research or applied basic research.

　　Key support projects

　　research direction:

　　1. Structural defect evolution mechanism and control method during the integral molding process of large-scale resin-based composite multi-rib curved surfaces (for application code 1, select the subordinate code of A08)

　　Facing the urgent need for high-performance composite integral molding manufacturing in the development of my country’s new generation of large aircraft, a thermal-fluid-solid multi-field coupling analysis model for co-solidification integral molding of composite multi-reinforced curved surface components was established to reveal internal delamination, The formation and evolution mechanism of structural defects such as resin unevenness and out-of-tolerance appearance are proposed, and a multi-dimensional optimization and control method for high-performance and accurate molding is proposed.

　　2. Practical magnetic flux pinning mechanism of superconducting materials and its enhancement method (for application code 1, select the subordinate code of E02)

　　Aiming at the problem of performance attenuation of superconducting materials in magnetic fields, we study the magnetic flux pinning mechanism of existing high-temperature and low-temperature superconducting materials, construct magnetic flux phase diagrams, identify the main magnetic flux pinning centers of different materials, and analyze the effects of magnetic flux quanta on thermal and Dynamic behavior under multi-field coupling conditions such as electricity and magnetism, a magnetic flux pinning enhancement method is proposed to improve the magnetic field current-carrying performance of superconducting materials.

　　3. Research on the structure and performance control of new high-entropy nanocomposite coatings (for application code 1, select the subordinate code of E01)

　　Facing the urgent demand for long-life, high-precision coating tools in precision machining, we study the micro-arc discharge characteristics of high-entropy targets, multi-dimensionally regulate the structure of dual-phase high-entropy nanocomposite coatings, and reveal the dual-phase, homogeneous multi-layer extremely hard and high The strengthening and toughening mechanism of entropy nanocomposite coatings clarifies the intrinsic mechanism of strong film-based interface bonding, providing scientific basis for the development and application of new tool coatings.

　　4. Research on the physical and chemical mechanism of purification of raw magnesium (for application code 1, select the subordinate code of E01)

　　In view of the problems that raw magnesium has many types of impurities, large content fluctuations, many oxidized inclusions, and the existing purification technology is high-cost and small-scale, the physical and chemical mechanisms and control methods of raw magnesium purification are studied, and the existence status of impurities in raw magnesium is analyzed to clarify The physical and chemical laws of impurity evolution during the purification process, and the development of large-scale, low-cost impurity and oxide control and removal methods.

　　5. Research on the mechanism and method of conformal assembly of complex shape, function and structure integration (for application code 1, select the subordinate code of E05)

　　Facing the urgent need for integrated manufacturing of complex-shaped functional structures such as conformal antennas for aerospace vehicles, carry out research on high-performance assembly mechanisms and methods, reveal the conformal printing interface bonding mechanism, defect formation rules and suppression mechanisms, and establish the accuracy of multi-field coupling- Functional integration prediction model proposes a high-performance integrated conformal assembly method of functional structures.

　　6. Preparation of high-performance binary poorly miscible metals and research on arc action mechanism (for application code 1, select the subordinate code of E01)

　　In response to the need to improve the service performance of key materials such as tungsten copper and niobium titanium used in power transmission and transformation and aerospace equipment, research on common technologies such as ablation behavior and melting rules of binary poorly miscible metals under strong arc action was carried out to reveal the material strengthening mechanism and service performance. The performance collaborative regulation mechanism forms a prototype of the preparation technology, providing a scientific basis for the application of high-performance binary poorly miscible metals in harsh environments.

　　7. Research on the controllable fabrication and spatiotemporal coordinated osseointegration mechanism of tantalum-titanium-based fusion cages adapted to biological parameters (for application code 1, select the subordinate code of E05)

　　Aiming at the mismatch between osseointegration and elastic modulus of implanted cages in patients with spinal degenerative diseases, we explore the strong bonding mechanism of the interface between the matrix and the coating, reveal the spatiotemporal synergistic regulation mechanism of osseointegration of composite cages, and propose a “bone adaptation” method for biological parameter adaptation. The controllable manufacturing method of tantalum-titanium-based fusion devices with integrated matrix and coating provides a scientific basis for the development and application of a new generation of high-performance fusion devices.

　　The above research directions encourage applicants to conduct cooperative research with universities, research institutions or enterprises with certain research strength and research conditions in Shaanxi Province.

　　5. Electronic information field

　　(1) In response to the major needs for the development of electronic information, artificial intelligence and other fields in Jiangsu Province, focusing on key scientific issues such as future network communications, core algorithms and future computing, artificial intelligence, new materials and new information devices, integrated circuits, and quantum information, Carry out relevant basic research or applied basic research.

　　Key support projects

　　research direction:

　　1. Satellite-ground integrated intelligent transmission theory and technology (for application code 1, select the subordinate code of F01)

　　In view of the challenges faced by satellite-ground integrated transmission such as channel model mismatch, high transmission complexity, and insufficient universality, large-dimensional channel statistical modeling and parameter estimation, channel knowledge map construction, and location information-assisted satellite-ground integration are studied. Theoretical methods such as key performance analysis of intelligent simplified transmission and air interface resource allocation are carried out to verify key technologies to provide theoretical and technical support for the construction of future satellite-ground integrated mobile communication systems.

　　2. High-speed wireless optical communication signal processing and networking theory technology (for application code 1, select the subordinate code of F01)

　　Facing the construction needs of future air, space, earth and sea communication networks, study the propagation characteristics of broadband wireless optical signals, explore theoretical technologies such as high-speed wireless optical signal modulation, optical beam forming and control, and intelligent wavelength selection, and break through low-complexity wireless optical signal processing under limited resources. Methods: Research high-speed, flexible and efficient wireless optical communication network networking technology to provide theoretical and technical support for multi-scenario and multi-service wireless optical communications.

　　3. Basic theories and methods of low-cost large models based on inheritable learning (for application code 1, select the subordinate code of F06)

　　Aiming at the key challenges of uncontrollable behavior, weak privacy protection, and high application threshold of current large models, the basic theory of low-cost large models based on inheritable learning is studied. Study the model expansion mechanism based on inheritable information between models, explore the efficient model adaptation mechanism that can dynamically match target task resources, and propose a large model training method based on cross-task common meta-information to provide high security, low cost, and strong privacy protection for deployment The large model provides theoretical and technical support.

　　4. Key technologies for robust perception and accurate prediction of driverless 3D environments (for application code 1, select the subordinate code of F06)

　　Facing the application needs in the field of autonomous driving, carry out research on the basic theory and key common technologies of driving environment perception and prediction, establish theories and methods integrating 3D depth perception, scene segmentation, target tracking, trajectory and occupation prediction, and perception decision-making, and improve Robustness, adaptability, accuracy and real-time performance of intelligent unmanned system perception and prediction in unstructured complex environments.

　　5. Research on the multi-scale control mechanism of environmentally friendly quantum dot luminescence (for application code 1, select the subordinate code of F04 or F05)

　　Aiming at the bottleneck problem of environmentally friendly quantum dot displays, study the multi-scale structure-activity relationship between ion orbits, size distribution, core-shell structure and luminescence performance, study the influence of interface quantum wells on excited states, and realize the high efficiency of environmentally friendly quantum dots. Luminous, providing theoretical foundation support for wide color gamut environmentally friendly displays.

　　6. Metasurface heterogeneous integrated two-dimensional material photoelectric imaging chip (for application code 1, select the subordinate code of F04 or F05)

　　To meet the application requirements of multi-dimensional light field sensing, research the intelligent design method of metasurfaces that respond to optical parameters such as wavelength, polarization, orbital angular momentum, etc., as well as the coupling mechanism with two-dimensional materials; break through the integration of large-scale optical metasurfaces and two-dimensional photodetection devices technology to develop multi-dimensional light field detection high-resolution monolithic integrated imaging chips.

　　7. Nitrogen polarity gallium nitride-based millimeter wave devices (for application code 1, select the subordinate code of F04)

　　Focusing on key issues such as epitaxial structure design and growth based on nitrogen polar gallium nitride materials, millimeter wave device technology, heterojunction carrier transport characteristics, etc., we will carry out energy band structure control and thin film epitaxy of core active region heterojunctions. Research on impurity control during growth, formation and regulation of surface/interface defects in device processes, and the mechanism of the effect of electric field on carrier mobility, etc., to develop high-performance nitrogen polar gallium nitride-based millimeter wave devices.

　　8. Research on low-dimensional room temperature multiferroic semiconductor materials (for application code 1, select the subordinate code of A20)

　　Aiming at the key bottleneck issues of the new generation of low-dimensional ferroic semiconductors such as low operating temperature and weak multiferroic coupling, study the novel spin and charge polarization behaviors in low-dimensional semiconductors, reveal the ferroic generation and strong coupling mechanisms in low-dimensional semiconductors, and achieve breakthroughs. Weak super-exchange interaction limits, study the preparation method of low-dimensional room temperature ferroic semiconductor materials, and provide theoretical support and technical support for the development of new low-dimensional semiconductor devices.

　　9. The theory and method of distributed control and decision-making based on privacy protection (for application code 1, select the subordinate code of F03)

　　Facing the objective needs of privacy protection in unmanned autonomous systems, study the basic theories of time-delay system stability analysis, distributed control, group intelligence collaborative reinforcement learning and distributed games based on privacy protection, and construct distributed control and decision-making under privacy protection. An integrated research framework provides theoretical and methodological support for basic research on swarm intelligence and information security.

　　10. Research on brain-inspired intelligent probabilistic computing devices and architecture (for application code 1, select the subordinate code of F04)

　　Facing the frontier of brain-like intelligence technology, carry out research on theoretical models of probabilistic computing based on brain information processing mechanisms; explore new materials and new states of matter suitable for probabilistic calculations; build probabilistic computing functional devices and corresponding technical architectures, and carry out functional verification of corresponding technologies .

　　11. Key technologies for silicon-based heterogeneous integrated high-speed terahertz detectors (for application code 1, select the subordinate code of F01)

　　Facing the development needs of terahertz integrated circuits, study the terahertz response enhancement mechanism of new Schottky diodes, reveal its efficient coupling mechanism with silicon-based waveguide circuits, break through thin-film chip transfer technology, and develop silicon-based heterogeneous integrated Schottky diodes Terahertz detectors provide key components and support for high-speed and large-capacity terahertz communication systems.

　　12. Research on the physical basis and application of optical quantum neural networks (for application code 1, select the subordinate code of A22)

　　Facing the development frontier of optical quantum neural networks, study the impact of multi-photon interference on expression ability, optimize cost function measurement methods and parameter update algorithms, establish a more flexible network structure, improve the performance of optical quantum neural networks, and demonstrate the role of optical quantum neural networks in data classification and Applications in quantum precision measurements.

　　13. Research on the phase modulation and mixing mechanism of terahertz waves based on gallium nitride two-dimensional electron gas devices (for application code 1, select the subordinate code of F01)

　　Facing the demand for active phased array chips in 6G terahertz communication sensing technology, we will conduct in-depth research on the design and growth of high-conductivity gallium nitride two-dimensional electron gas material structures based on the phase modulation and mixing detection mechanisms of terahertz waves. Key issues such as amplitude and phase modulation, frequency mixing and coherent array integration of high electron mobility transistors and Schottky barrier diodes provide key technical support for the realization of terahertz active phased array chips.

　　Applicants for the above research directions are encouraged to apply in cooperation with universities, research institutions or enterprises in Jiangsu Province that have certain research strength and research conditions.

　　(2) In response to the development needs of the electronic information field in Jiangxi Province, carry out basic research or applied basic research on image information processing, medical optics and photoelectric imaging.

　　Key support projects

　　research direction:

　　1. Research on the multi-scale change characteristics and space weather effects of the mid- and low-latitude ionosphere in complex space environments (for application code 1, select the subordinate code of D04)

　　Focusing on coupling mechanisms such as ionosphere/thermosphere photochemistry and dynamics, we integrate numerical and data analysis, and apply cutting-edge technologies such as data assimilation and deep learning to study the multi-spatial and temporal scale physical processes of the ionosphere/thermosphere driven by solar storms, focusing on exploring medium and low Characteristics of different types of disturbances in the latitudinal ionosphere and thermosphere and regional characteristics of medium and small-scale structures, carry out high-precision modeling and forecasting of the ionosphere and thermosphere, and serve Beidou for accurate, continuous and real-time positioning.

　　2. Optoelectronic imaging and display integration technology for generative artificial intelligence (for application code 1, select the subordinate code of F05)

　　For target perception and VR/AR efficient representation of generative artificial intelligence, study the intelligent optimization design method of modulated lighting-detection imaging-VR/AR display integrated system, explore three-dimensional high spatial and temporal resolution information perception of non-line-of-sight targets, and realize photoelectric Imaging and display integration.

　　3. High-quality virtual and real integration technology for cross-media dynamic scenes (for application code 1, select the subordinate code of F01)

　　In order to solve the problems of uncoordinated fusion of virtual and real scenes, difficulty in interaction, and data security threats, research on high-quality generation of multimedia dynamic elements and virtual and real fusion technology to achieve immersive experience in virtual and real fusion scenes; explore cross-media feedback mechanisms to achieve intelligent interaction and dynamics in virtual and real fusion scenes. Update: Research virtual forged data monitoring methods to ensure data authenticity in virtual and real integration scenarios. Achieve high-quality virtual and real integration of cross-media dynamic scenes.

　　4. Brain tissue longitudinal modulus and shear modulus optical elastography technology (for application code 1, select the subordinate code of F05)

　　In response to the need for non-contact and high-resolution detection imaging of brain tissue lesions, we conduct optical coherence elastography research on the longitudinal modulus and shear modulus of brain tissue, and explore the light energy threshold and air-coupled excitation energy threshold of brain tissue stimulated Brillouin elastography. mechanism to achieve optical multi-modal elastic high-resolution imaging of brain tissue.

　　Applicants outside Jiangxi Province for the above research directions should apply in cooperation with universities, research institutions or enterprises in Jiangxi Province that have certain research capabilities and conditions.

　　(3) Carry out basic research or applied basic research around the major needs for the development of the electronic information and communications industry in Shaanxi Province, focusing on key scientific issues in cloud computing and future networks, high-performance computing and artificial intelligence, microelectronics and optoelectronics.

　　Key support projects

　　research direction:

　　1. Research on ultra-lightweight and energy-efficient on-chip self-learning algorithm and architecture co-design method (for application code 1, select the subordinate code of F04)

　　Facing the need to improve the autonomous capabilities of unmanned systems in complex environments, research on ultra-lightweight self-learning algorithms and high-energy-efficiency on-chip self-learning architecture and circuits, and propose a low-data-dependent self-learning model parameter update mechanism, on-chip push and training multi-task integrated computing architecture, Efficient storage bandwidth compression circuit, etc., complete the design of field programmable gate array (FPGA) and its application verification on unmanned systems.

　　2. Collaborative design of high-performance multi-functional integrated flexible electronic devices (for application code 1, select the subordinate code of F04)

　　In view of the demand for multi-functional integrated flexible electronic devices in smart wearable equipment, explore multi-material and cross-scale mechanical calculation simulation collaborative optimization methods, study new light-curing 3D printing structures, reveal the influence of flexible materials on device performance, and achieve high-performance multi-functional Dimensionally integrated flexible energy storage, sensing, wireless charging and thermal management devices.

　　3. Research on the electromagnetic anti-reflection mechanism of multi-resonance mode synergy of metamaterials (for application code 1, select the subordinate code of F01)

　　In response to the demand for high-performance electromagnetic wave-transparent materials in high-speed aircraft antenna systems, the multi-resonance mode synergistic metamaterial electromagnetic anti-reflection technology is studied, the large incident angle/broadband electromagnetic anti-reflection mechanism is revealed, and a metamaterial electromagnetic anti-reflection design method is proposed to achieve composite Sample development and performance verification of electromagnetic anti-reflection materials.

　　4. Research on self-excited large-bandwidth tunable high-precision optical frequency control in complex environments (for application code 1, select the subordinate code of F05)

　　Focusing on the requirements for autonomous operation of light sources that are immune to complex environments and large bandwidth in the construction of high-precision ground-based timing systems, we study the self-excited high-dynamic optical frequency control mechanism, build a core technology system for automatic control of high-precision optical frequency sources, and develop a ground-based timing system that meets the requirements The required engineering prototype realizes a high-performance sub-hertz optical frequency signal source.

　　5. Research on vehicle-road-cloud collaborative computing methods for autonomous driving (for application code 1, select the subordinate code of F02)

　　Based on the spatiotemporal characteristics of autonomous driving tasks under different terrains, build a vehicle-road-cloud collaborative computing information model and integrated architecture that supports multiple driving scenarios, reveal the element coupling mechanism and operating mechanism of vehicle-road-cloud collaborative computing, and study low latency and high concurrency. Chelu-Cloud collaborative computing and task scheduling technology enables large-scale testing and verification of atypical scenarios.

　　6. Research on the cross-scale fusion mechanism of terahertz chip modules for space applications (for application code 1, select the subordinate code of F04)

　　In view of the demand for terahertz all-solid-state chips and modules for large-capacity and high-speed space communications, reveal the carrier transport mechanism and nano-channel modulation mechanism of semiconductor devices in the terahertz frequency band, and study the chip micron-scale interconnection transmission mechanism and multi-channel modulation mechanism. Functionally high-density integrated multi-modal control theory to build a cross-scale three-dimensional integrated fusion system for terahertz transceiver front-end.

　　The above research directions encourage applicants to conduct cooperative research with universities, research institutions or enterprises with certain research strength and research conditions in Shaanxi Province.

　　6. Population and Health Field

　　(1) Focusing on the life and health needs of the people of Jiangsu Province and facing the major needs of the development of modern medicine and biopharmaceutical industries, carry out basic research on key scientific issues such as drug lead compounds, in vivo organoid construction, and immune imbalance mechanisms of viral diseases. or applied basic research.

　　Key support projects

　　research direction:

　　1. Discovery of potential new targets for anti-diabetic foot based on clinical samples and design, synthesis and optimization of novel drug lead compounds (for application code 1, select the subordinate code of H34)

　　Utilize clinical samples and adopt multidisciplinary technical means to identify the core proteins involved in the development of diabetic foot, conduct research on the corresponding pathological mechanisms, discover potential new targets for anti-diabetic foot, and carry out the design, synthesis and optimization of drug lead compounds for the new targets.

　　2. Construction of mouse humanized organoids and research on the steady-state regulation mechanism of organ development (for application code 1, select the subordinate code of C12)

　　Based on organoids constructed from human stem cells and human tissues, combined with technologies such as mouse immune system humanization, we will establish in vivo organoids with complex tissue microenvironments and physiological structures such as immunity, metabolism, and circulation, and analyze their development processes. It reveals the dynamic relationship between physiological homeostasis, disease occurrence and development, and key processes of human organoid development, and provides innovative technology and theoretical support for the construction of systemic tissues and organs.

　　3. Research on the immune imbalance mechanism and intervention strategies of viral infection (for application code 1, select the subordinate code of C08)

　　Taking major viral diseases as the research object, using organoids, animal models and clinical specimens, we will explore the impact of viral infection on the body’s immune system and reveal the mechanism by which anti-viral immunity and immune imbalance lead to body damage; design and discover new types of immune intervention antibodies. Viral drug candidates lay the foundation for the development of new intervention strategies for viral diseases.

　　4. Research on the functional material basis and mechanism of action of bitter traditional Chinese medicines with immunomodulatory function (for application code 1, select the subordinate code of H32)

　　Aiming at the common clinical inflammatory diseases, bitter traditional Chinese medicines with the functions of clearing away heat and detoxifying, lowering qi and resolving phlegm, promoting qi and relieving pain, etc. are selected, and multidisciplinary methods and technologies are used to establish a pharmacodynamic evaluation model corresponding to the efficacy to clarify the efficacy of bitter traditional Chinese medicines. material basis, reveal its immune regulatory targets and mechanisms of action on the occurrence and development of diseases, and on this basis, carry out the discovery and druggability research of original new drug candidates.

　　5. Research on early and accurate assessment and repair of local radiation damage (for application code 1, select the subordinate code of H29)

　　Focusing on the key points and difficulties in the diagnosis and treatment of local radiation injury, based on technologies such as intelligent responsive imaging probes, we will explore and establish a new system for early and accurate assessment of the degree of local radiation damage, lesion range and radiation dose, and study the targeting of key cells and tissue microorganisms for local radiation damage. Methods and mechanisms for early environmental intervention and repair have achieved key breakthroughs in the diagnosis and treatment of local radiation injuries.

　　6. The neural circuit mechanism of the core symptoms of autism or adolescent mood disorders (for application code 1, select the subordinate code of H09 or H10)

　　Focusing on autism or adolescent mood disorders, through the construction and use of animal models, we analyze the neural circuit basis of the core symptoms of the above diseases, explore the molecular and cellular mechanisms by which factors such as genetic variation lead to the core symptoms of related diseases, and develop new drugs and physical intervention strategies. Provide scientific basis for intervention and treatment of related diseases.

　　7. The interaction and evolution of mesenchymal stem cells and tissue microenvironment during the disease process (for application code 1, select the subordinate code of C12)

　　Focusing on the maintenance mechanism of tissue immune homeostasis, we focus on the cell interaction characteristics of mesenchymal stem cells involved in tissue immune homeostasis, and elucidate that imbalance in their homeostasis affects the occurrence and development of major chronic diseases such as lung/liver fibrosis, autoimmune diseases, and heart disease. key link, reveal the molecular mechanisms in cell interaction and evolution, and explore new methods for the treatment of related major chronic diseases.

　　Applicants for the above research directions are encouraged to apply in cooperation with universities, research institutions or enterprises in Jiangsu Province that have certain research strength and research conditions.

　　(2) Based on the development needs of the population and health fields in Shaanxi Province, carry out basic research or applied basic research on the pathogenesis, precise diagnosis and treatment of major diseases, rare diseases and high incidence in areas, as well as key scientific issues in the development and utilization of Qin medicines.

　　Key support projects

　　research direction:

　　1. Construction of standardized xenogeneic liver transplantation model and research on long-term survival mechanism (for application code 1, select the subordinate code of H03)

　　Based on gene editing technology, establish standardized large animal models of xenogeneic auxiliary and orthotopic liver transplantation, evaluate their effectiveness and safety, and explore the molecular mechanisms that trigger pathological processes such as physiological compatibility, immune rejection, coagulation disorders, and inflammatory injury of xenogeneic liver transplantation. Find potential intervention targets, develop effective intervention strategies, and extend the functional survival time of grafts and recipients.

　　2. Research on the functional substance analysis and quality formation mechanism of Shaanxi’s special medicinal and edible Qin medicine (for application code 1, select the subordinate code of H32)

　　Select 2 to 3 Shaanxi special medicinal and edible Qin medicines as key research objects, clarify their main functional ingredient groups and quality markers, analyze the formation mechanism of excellent quality, reveal the relevant action mechanism of functional ingredients, and explore the resources of non-medicinal parts The comprehensive utilization value provides scientific basis for the guarantee and sustainable utilization of high-quality resources of Qin medicine for both medicinal and food purposes.

　　3. The mechanism of allergic rhinitis caused by volatile substances of Artemisia plants and the discovery of anti-allergic active molecules of traditional Chinese medicine (for application code 1, select the subordinate code of H32)

　　In view of the prominent problem of high incidence of allergic rhinitis caused by Artemisia plants in northern Shaanxi, screening, analysis, identification and sensitization evaluation of volatile allergens of Artemisia plants were carried out to clarify its mechanism of action leading to allergic rhinitis; to establish target-based anti-allergic activity Efficient ingredient screening method discovers active molecules of anti-allergic traditional Chinese medicine and reveals their mechanism of action, laying the foundation for research on candidate drugs for the treatment of allergic rhinitis.

　　4. Research on the pathogenesis and precise diagnosis and treatment strategies of neuroimmune diseases (for application code 1, select the subordinate code of H09)

　　Aiming at the unclear mechanisms of neuroimmune diseases and the lack of auxiliary diagnostic methods and targeted drugs, we combine clinical resources and animal models to reveal the pathogenesis and potential intervention targets of neuroimmune diseases; use clinical cohorts and biobanks to establish New technology for real-time autoantibody detection, screening biomarkers for disease early warning, progression, and efficacy evaluation, providing a basis for precise diagnosis and treatment of neuroimmune diseases.

　　The above research directions encourage applicants to conduct cooperative research with universities, research institutions or enterprises with certain research strength and research conditions in Shaanxi Province.

　　7. Application requirements

　　(1) Applicant conditions.

　　Applicants should meet the following conditions:

　　1. Have experience in undertaking basic research projects or other basic research;

　　2. Hold senior professional and technical positions (professional titles);

　　Postdoctoral researchers at the station, those who are pursuing a graduate degree, and those who do not have an employer or whose unit is not a supporting unit are not allowed to apply as applicants.

　　(2) Regulations on limited applications.

　　Implement the relevant requirements of the limited application provisions in the “Application Regulations” of the “2024 National Natural Science Foundation of China Project Guide”.

　　8. Things to note when applying

　　Applicants and supporting institutions should carefully read and implement the relevant requirements in this project guide, the “2024 National Natural Science Foundation of China Project Guide” and the “Notice on 2024 National Natural Science Foundation of China Project Application and Finalization and Other Related Matters”.

　　1. This joint fund project adopts paperless application. The application submission time is from April 15 to 16:00 on April 20, 2024.

　　2. This joint fund is open to the whole country and competes fairly. For cooperative research projects, the cooperation content and main division of labor of the cooperating parties should be clearly stated in the application. The number of cooperative research units for key support projects shall not exceed 2.

　　3. Applicants can only apply for one Regional Innovation and Development Joint Fund project in the same year.

　　4. The applicant logs in to the National Natural Science Foundation of China Network Information System (referred to as the information system) and writes the application online. Applicants who do not have an information system account should apply to the fund management contact person of the supporting unit to open an account.

　　5. Select “Joint Fund Project” for the funding category in the application, select “Key Support Projects” for the subcategory description, and select “Regional Innovation and Development Joint Fund” for “Notes”; “Application Code 1” should be in accordance with this Joint Fund Project Guide Required selection, “Application Code 2” independently selects the corresponding application code according to the project research field; “Field Information” selects the corresponding field name according to the project research field, such as “Biology and Agriculture”; “Main Research Direction” according to the project research direction Select the corresponding direction name, such as “1. Research on the regulation mechanism of acidic polysaccharide biosynthesis and structural modification”, and the research period should be filled in “January 1, 2025 – December 31, 2028”.

　　6. The applied project should comply with the funding scope and requirements of this project guide. Applicants write applications according to the project application writing outline. If the applicant has already undertaken other national science and technology plan projects related to this joint fund project, the differences and connections between the applied project and other related projects should be discussed in the “Research Basis and Working Conditions” section of the main body of the application.

　　7. The research results obtained by funded projects, including published papers, monographs, research reports, software, patents, awards and achievement reports, etc., should indicate the project funding and project approval number of the National Natural Science Foundation of China Regional Innovation Development Joint Fund or make relevant illustrate. The National Natural Science Foundation of China and Jiangsu, Jiangxi, Shaanxi and other provinces jointly promote project data sharing and local promotion and application of research results.

　　8. The host unit shall complete the host unit’s commitment letter, organization application, and review of application materials as required. Submit the unit’s electronic application and attachment materials through the information system item by item before 16:00 on April 20, 2024, and submit the unit’s project application list online before 16:00 on April 21.

　　Contact information

　　National Natural Science Foundation of China Planning and Policy Bureau

　　Contact person: Li Zhilan Liu Quan

　　Tel: 010-62329897, 62326872

　　Jiangsu Provincial Department of Science and Technology

　　Contact person: Fan Jun, Li Yafang

　　Tel: 025-83214956

　　Jiangxi Provincial Department of Science and Technology

　　Contact person: Wang Zhiqiang Yan Xiang

　　Tel: 0791-86252914, 86266641

　　Shaanxi Provincial Department of Science and Technology

　　Contact person: Zhang Gao Gaoyun

　　Tel: 029-87294395, 81129231