Particle Size & Zeta Potential Analyzer

Model:

Brookhaven NanoBrook 90plus PALS

Location:

R402

Main parameters:

  • Size Range:
    • Sizing: 0.3 nm to 10 µm diameter, depending on refractive index and concentration
    • Zeta potential: 1 nm to 100 µm, sample dependent
    • Molecular Weight: 9,800 Da to 20 MDa, sample dependent
  • Mobility Range: 10−11 to 10−7 m2/(V·s)
  • Zeta potential range: -500 mV to 500 mV, sample dependent
  • Maximum sample conductivity:
    • Sizing: unlimited
    • Zeta potential: 220 mS/cm
  • Concentration Range:
    • Sizing: 0.1 ppm to 50 mg/mL, depending on refractive index and concentration
    • Zeta potential: 40% w/v, sample dependent
  • Signal Processing:
    • Sizing: Dynamic Light Scattering, DLS
    • Zeta potential: Electrophoretic & true Phase Analysis Light Scattering, ELS & PALS
    • Molecular Weight: SLS Debye Plot & MHS Parameters (DLS)
  • Precision:
    • Sizing: ± 1% typical
    • Zeta potential: ± 3% typical
  • Accuracy:
    • Sizing: ± 2% on NIST traceable latex standards
    • Zeta potential: 2.53 ± 0.12 µm • cm/V • s for aqueous systems with NIST SRM1980
    • Molecular Weight: ± 10% typical
  • Standard Laser: 40 mW 640 nm temperature-controlled red semiconductor laser. Alternative wavelengths available.
  • Scattering Angle: 90° & 15°

Typical applications:

This package not only allows rapid measurements of the effective size and zeta potential of samples, but also provides further information on multimodal size distributions.NanoBrook 90Plus PALS guarantees excellent mobility measurement performance in low to high salt aqueous suspensions and non-polar liquids.

  • Rapid and accurate nanoparticle size distributions
  • For proteins, peptides, mAb, RNA, and other biological samples
  • For high salt, organic solvents & viscous media

Sample requirements:

Sizing: nano particle and colloidal-sized materials, in any non-absorbing liquid.

Zeta potential: proteins, nanoparticle, polymer, and colloidal-sized materials, suspended in any non-absorbing liquid, with relative permittivity (dielectric constant) >1.5 and viscosity <30 cP.