Innate immunity and adaptive immune responses. Antibody classes and sub-classes, structure and function. Genetics and biosynthesis of immunoglobulins. Definitions of isotype allotype, idiotype. Hybridomas. Complement in humoral immunity and inflammation. Antibody based immuno-assays. The Major histocompatibility complex genetics, function and assays. The nature of antigen. The lymphatic system organs, tissues, cells. Genetics and specific of the T-cell receptor. The immune response cells and biological functions. Accessory cells. Cytokines and lymphokines. Inflammation and adhesion molecules. Cellular migration and cell - cell interactions. Natural and acquired tolerance. Autoimmunity, biology of transplantation. Allergies and hypersensitivities. AIDS. Mucosal immunity. Resistance to infection. Immunity of the newborn. The molecular basis of primary immunodeficiencies. 

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